Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 18/20 | 0.45 |
| ▸ | RXRB | P28702 | 13/20 | 0.41 |
| ▸ | RXRG | P48443 | 13/20 | 0.41 |
| ▸ | RARG | P13631 | 6/20 | 0.41 |
| ▸ | RARB | P10826 | 5/20 | 0.41 |
| ▸ | RARA | P10276 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771646 | 0.89 | RXRA (0.41) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7771786 | 0.85 | RXRA (0.44) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL6734814 | 0.83 | RXRA (0.58) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL6733785 | 0.81 | RXRA (0.46) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL9200174 | 0.77 | RXRA (0.50) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7771769 | 0.77 | RXRA (0.44) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7801892 | 0.76 | RXRA (0.58) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7769613 | 0.74 | RXRA (0.40) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL8093205 | 0.74 | RARB (0.50) | RXRARXRBRXRGRARGRARB | |
| SCHEMBL7773881 | 0.73 | CYP26B1 (0.42) | RXRARXRBRXRGRARGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823903-B1 | HETEROCYCLIC DIARYL COMPOUNDS, PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING SAME, AND USES THEREOF | CT INTERNAT DE RECH S (FR) | 2001-07-18 | — | — | EP | claimed |