Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | UGCG | Q16739 | 1/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771962 | 0.73 | CA1 (0.39) | TDP1MITFL3MBTL1GBA1UGCG | |
| SCHEMBL7775649 | 0.73 | CA1 (0.38) | TDP1MITFL3MBTL1GBA1UGCG | |
| SCHEMBL27629296 | 0.69 | TDP1 (0.51) | TDP1MITFL3MBTL1DPP4CA1 | |
| SCHEMBL8654796 | 0.68 | MITF (0.57) | TDP1MITFSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2587081 | 0.67 | CA1 (0.43) | CA1CA2CA4CA9 | |
| SCHEMBL5032600 | 0.67 | CA1 (0.38) | CA1CA2CA4CA9 | |
| SCHEMBL27629297 | 0.67 | MITF (0.50) | TDP1MITFL3MBTL1CA1CA2 | |
| SCHEMBL5695792 | 0.66 | TDP1 (0.47) | TDP1MITFL3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL21358777 | 0.66 | TAAR1 (0.35) | CA1CA2CA4CA9 | |
| SCHEMBL4649567 | 0.66 | SLC6A2 (0.50) | TDP1MITFCA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690051-B1 | DIAZACYCLOALKANEALKYLSULFONAMIDE DERIVATIVE | AZWELL INC (JP) | 2001-07-18 | — | — | EP | disclosed |
| US-5716950-A | NONTOXIC ANTIALLERGEN AND ANTIASTHMATIC HAVING LOW ANTIHISTAMINIC SIDE EFFECTS | NIPPON SHOJI KABUSHIKI KAISHA (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0690051-A1 | DIAZACYCLOALKANEALKYLSULFONAMIDE DERIVATIVE | NIPPON SHOJI KABUSHIKI KAISHA (JP) | 1996-01-03 | — | — | EP | disclosed |