Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.38 |
| ▸ | CHIA | Q9BZP6 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | UGCG | Q16739 | 1/20 | 0.32 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771962 | 0.99 | CA1 (0.39) | CA1CA2CA4CA9TDP1 | |
| SCHEMBL5695790 | 0.80 | TDP1 (0.45) | CA1CA2CA4CA9TDP1 | |
| SCHEMBL8073886 | 0.79 | GBA1 (0.35) | CHIT1CHIAADRA1DADRA1AADRA1B | |
| SCHEMBL5695792 | 0.78 | TDP1 (0.47) | TDP1L3MBTL1CHIT1CHIAMITF | |
| SCHEMBL2116076 | 0.76 | TDP1 (0.44) | CA1CA2CA4CA9TDP1 | |
| SCHEMBL7105280 | 0.76 | CHIT1 (0.34) | CHIT1CHIAMLNR | |
| SCHEMBL8571349 | 0.73 | CHIT1 (0.34) | CHIT1CHIAMITFSLC6A2SLC6A4 | |
| SCHEMBL28861068 | 0.73 | SLC6A2 (0.47) | TDP1L3MBTL1CHIT1CHIAMITF | |
| SCHEMBL3738377 | 0.73 | TDP1 (0.41) | TDP1L3MBTL1CHIT1CHIAMITF | |
| SCHEMBL7771886 | 0.73 | TDP1 (0.42) | CA1CA2CA4CA9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690051-B1 | DIAZACYCLOALKANEALKYLSULFONAMIDE DERIVATIVE | AZWELL INC (JP) | 2001-07-18 | — | — | EP | disclosed |
| EP-0690051-A1 | DIAZACYCLOALKANEALKYLSULFONAMIDE DERIVATIVE | NIPPON SHOJI KABUSHIKI KAISHA (JP) | 1996-01-03 | — | — | EP | disclosed |