Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123028 | 0.89 | F2 (0.44) | F2PRSS1SMN1; SMN2EGFRERBB2 | |
| SCHEMBL7767880 | 0.82 | F2 (0.61) | F2PRSS1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7771927 | 0.78 | KDM4E (0.44) | SMN1; SMN2KDM4EALDH1A1GAAKMT2A | |
| SCHEMBL7773563 | 0.78 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EALDH1A1KMT2ALMNA | |
| Propane SCHEMBL8178139 | 0.78 | KIF18A (0.41) | F2PRSS1SMN1; SMN2EGFRERBB2 | |
| SCHEMBL7772059 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4EALDH1A1GAAKMT2A | |
| SCHEMBL7773566 | 0.77 | MAPT (0.44) | SMN1; SMN2KDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL7772077 | 0.74 | MAPT (0.37) | SMN1; SMN2KDM4EALDH1A1KMT2ALMNA | |
| SCHEMBL7772056 | 0.73 | PDE4B (0.41) | SMN1; SMN2KDM4EALDH1A1KMT2APOLB | |
| SCHEMBL7773817 | 0.72 | F2 (0.45) | F2PRSS1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |