Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380155 | 0.90 | ALDH1A1 (0.34) | MAPTHTTALDH1A1ESR2LMNA | |
| SCHEMBL7772062 | 0.85 | RAB9A (0.39) | MAPTHTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL7772056 | 0.80 | PDE4B (0.41) | MAPTPOLBHTTKDM4ESMN1; SMN2 | |
| SCHEMBL8118422 | 0.80 | ALDH1A1 (0.33) | MAPTHTTALDH1A1LMNAMAPK1 | |
| SCHEMBL7773563 | 0.78 | SMN1; SMN2 (0.44) | MAPTPOLBHTTKDM4ESMN1; SMN2 | |
| SCHEMBL7773566 | 0.77 | MAPT (0.44) | MAPTPOLBHTTKDM4ESMN1; SMN2 | |
| SCHEMBL7772045 | 0.74 | F2 (0.44) | MAPTPOLBHTTKDM4ESMN1; SMN2 | |
| SCHEMBL7771637 | 0.72 | SMN1; SMN2 (0.41) | MAPTPOLBHTTKDM4ESMN1; SMN2 | |
| SCHEMBL7214195 | 0.72 | ALDH1A1 (0.42) | KDM4EALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL7771927 | 0.72 | KDM4E (0.44) | MAPTPOLBHTTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252082-B1 | CARDIOVASCUALR DISORDERS | SANOFI-SYNTHELABO (FR) | 2001-06-26 | — | — | US | disclosed |