SCHEMBL775141

SCHEMBL775141

Cc1ccc(C(=O)SC(=O)c2ccc(C)cc2C)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.49
NFE2L2 Q16236 1/20 0.46
SMN1; SMN2 Q16637 5/20 0.45
HTT P42858 1/20 0.45
HSD11B1 P28845 1/20 0.44
TP53 P04637 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
NPC1 O15118 5/20 0.42
RAB9A P51151 5/20 0.42
MAPT P10636 2/20 0.41
PKM P14618 1/20 0.41
FLT1 P17948 1/20 0.41
FLT4 P35916 1/20 0.41
KDR P35968 1/20 0.41
MEN1 O00255 2/20 0.41
CSNK2A1 P68400 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
TAS1R2 Q8TE23 1/20 0.41
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31369141 0.79 LMNA (0.50) KMT2ANFE2L2SMN1; SMN2HTTHSD11B1
SCHEMBL286054 0.79 LMNA (0.50) KMT2ANFE2L2SMN1; SMN2HTTHSD11B1
SCHEMBL9420260 0.79 NFE2L2 (0.55) KMT2ANFE2L2SMN1; SMN2HTTHSD11B1
SCHEMBL11002201 0.79 CSNK2A1 (0.57) KMT2ANFE2L2SMN1; SMN2MEN1CSNK2A1
SCHEMBL28674201 0.79 KMT2A (0.43) KMT2ANFE2L2SMN1; SMN2HTTHSD11B1
SCHEMBL7772519 0.79 NFE2L2 (0.44) KMT2ANFE2L2SMN1; SMN2HTTHSD11B1
SCHEMBL775486 0.78 HSD17B1 (0.39) KMT2ASMN1; SMN2HTTNPC1RAB9A
SCHEMBL8401162 0.77 NFE2L2 (0.50) KMT2ANFE2L2SMN1; SMN2HTTHSD11B1
SCHEMBL96218 0.77 KMT2A (0.51) KMT2ANFE2L2SMN1; SMN2HTTHSD11B1
SCHEMBL107259 0.77 CSNK2A1 (0.59) KMT2ANFE2L2SMN1; SMN2HTTHSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9343777-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-05-17 US disclosed
US-9252457-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2016-02-02 US disclosed
US-20120177988-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-07-12 US disclosed
US-20120070731-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2012-03-22 US disclosed