Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ACP1 | P24666 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7456635 | 0.81 | LMNA (0.55) | LMNAACP1PKMTSHRALDH1A1 | |
| SCHEMBL13451652 | 0.79 | LMNA (0.60) | LMNAACP1PKMTSHRALDH1A1 | |
| SCHEMBL5170201 | 0.79 | MAPT (0.42) | ALDH1A1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3147418 | 0.79 | LMNA (0.64) | LMNAACP1PKMTSHRALDH1A1 | |
| SCHEMBL3814075 | 0.76 | LMNA (0.56) | LMNAACP1PKMTSHRALDH1A1 | |
| SCHEMBL1110900 | 0.76 | TSHR (0.41) | LMNATSHRMAPK1 | |
| SCHEMBL8358624 | 0.74 | GRM5 (0.51) | LMNAACP1PKMTSHRALDH1A1 | |
| SCHEMBL4649145 | 0.74 | LMNA (0.49) | LMNAACP1PKMTSHRALDH1A1 | |
| SCHEMBL5792650 | 0.72 | LMNA (0.55) | LMNAACP1PKMTSHRALDH1A1 | |
| SCHEMBL1515690 | 0.72 | LMNA (0.55) | LMNAACP1PKMTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119560-A1 | NAPHTHOPYRANS ANNELATED IN C5-C6, THEIR PREPARATION AND COMPOSITIONS AND (CO) POLYMER MATRICES CONTAINING THEM | Corning S.A. (FR) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000015628-A1 | NAPHTHOPYRANS ANNELATED IN C5-C6, THEIR PREPARATION AND COMPOSITIONS AND (CO) POLYMER MATRICES CONTAINING THEM | CORNING S.A. (FR) | 2000-03-23 | — | — | WO | disclosed |