Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4857099 | 0.84 | MAPT (0.52) | MAPTSMN1; SMN2MAPK1L3MBTL1MEN1 | |
| SCHEMBL1819239 | 0.81 | MAPT (0.41) | MAPTSMN1; SMN2MAPK1L3MBTL1MEN1 | |
| SCHEMBL7772156 | 0.79 | LMNA (0.51) | MAPTSMN1; SMN2MAPK1L3MBTL1MEN1 | |
| SCHEMBL4857289 | 0.76 | GAA (0.57) | MAPTSMN1; SMN2MAPK1L3MBTL1KDM4E | |
| SCHEMBL15906526 | 0.74 | MAPT (0.48) | MAPTSMN1; SMN2MAPK1L3MBTL1NPC1 | |
| SCHEMBL1813801 | 0.73 | ALDH1A1 (0.42) | MAPTSMN1; SMN2MAPK1L3MBTL1MEN1 | |
| SCHEMBL24605276 | 0.72 | MAPT (0.43) | MAPTSMN1; SMN2MAPK1L3MBTL1MEN1 | |
| SCHEMBL15906559 | 0.71 | MAPT (0.47) | MAPTSMN1; SMN2MAPK1L3MBTL1MEN1 | |
| SCHEMBL25091076 | 0.70 | MAPT (0.41) | MAPTSMN1; SMN2MAPK1L3MBTL1MEN1 | |
| SCHEMBL24403964 | 0.70 | MAPT (0.42) | MAPTSMN1; SMN2MAPK1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776436-A1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006022825-A1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2006-03-02 | — | — | WO | disclosed |