SCHEMBL7772164

SCHEMBL7772164

OC(F)(F)CF.c1ccc2cccc-2cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.46
ALDH1A1 P00352 2/20 0.45
PTPN5 P54829 3/20 0.42
PTPN1 P18031 3/20 0.42
TAAR1 Q96RJ0 1/20 0.41
CYP2C9 P11712 1/20 0.40
MMP3 P08254 1/20 0.40
BCL2L1 Q07817 1/20 0.40
GGPS1 O95749 2/20 0.38
HDAC6 Q9UBN7 2/20 0.37
TSHR P16473 2/20 0.37
ABCC4 O15439 1/20 0.37
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37
PTGS1 P23219 1/20 0.37
HTT P42858 1/20 0.37
MGLL Q99685 1/20 0.37
MAOA P21397 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL27323950 0.81 ALDH1A1 (0.53) KIF11ALDH1A1PTPN5PTPN1TAAR1
Biphenyl SCHEMBL27485574 0.81 ALDH1A1 (0.60) KIF11ALDH1A1PTPN5PTPN1TAAR1
Toluene SCHEMBL8139791 0.78 LMNA (0.52) KIF11ALDH1A1TSHRLMNAHTT
Biphenyl SCHEMBL8089799 0.75 KIF11 (0.46) KIF11ALDH1A1PTPN5PTPN1TAAR1
Biphenyl SCHEMBL23430128 0.74 ALDH1A1 (0.69) KIF11ALDH1A1TAAR1MMP3BCL2L1
Benzene SCHEMBL26127054 0.73 CES1 (0.36)
Biphenyl SCHEMBL27620162 0.72 KIF11 (0.48) KIF11ALDH1A1PTPN5PTPN1TAAR1
Trifluoroacetic Acid SCHEMBL12611414 0.72 CES1 (0.52) KIF11ALDH1A1PTPN5PTPN1CYP2C9
Biphenyl SCHEMBL27543247 0.72 ALDH1A1 (0.64) KIF11ALDH1A1PTPN5PTPN1TAAR1
Benzene SCHEMBL6754211 0.71 ALDH1A1 (0.90) ALDH1A1TAAR1MMP3BCL2L1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2001169798-A METHOD FOR PRODUCING BOTH ENANTIOMERS OF OPTICALLY ACTIVE AZULENE TRIFLUOROETHANOL DERIVATIVE BY USE OF LIPASE KONAN KAKO KK 2001-06-26 JP disclosed