Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 6/20 | 0.56 |
| ▸ | DRD1 | P21728 | 3/20 | 0.56 |
| ▸ | DRD4 | P21917 | 3/20 | 0.56 |
| ▸ | DRD5 | P21918 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 5/20 | 0.52 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4484633 | 0.78 | MEN1 (0.57) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL4481567 | 0.78 | MEN1 (0.57) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL4478052 | 0.78 | MEN1 (0.61) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL2322967 | 0.75 | HTR1B (0.67) | MEN1KMT2ALTA4H | |
| SCHEMBL7773943 | 0.74 | MEN1 (0.51) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL29447351 | 0.74 | LTA4H (0.87) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL6393260 | 0.73 | LTA4H (0.84) | HRH1DRD1DRD4DRD5DRD3 | |
| SCHEMBL2329109 | 0.72 | ALDH1A1 (0.67) | MEN1KMT2ALTA4HHTT | |
| SCHEMBL2322184 | 0.72 | LTA4H (0.61) | MEN1KMT2ALTA4HHTT | |
| SCHEMBL6593991 | 0.72 | MEN1 (0.85) | MEN1KMT2ALTA4HHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265575-B1 | THROMBIN INHIBITORS | ELI LILLY AND COMPANY | 2001-07-24 | — | — | US | disclosed |
| US-6251921-B1 | ADMINISTERING THROMBIN INHIBITING DIAMINE COMPOUND TO MAMMAL | ELI LILLY AND COMPANY | 2001-06-26 | — | — | US | disclosed |
| US-6025382-A | Antithrombotic diamines | ELI LILLY AND COMPANY (US) | 2000-02-15 | — | — | US | disclosed |