Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3770252 | 1.00 | TNKS2 (0.33) | TNKS2PBRM1GPR3HTR2A | |
| Hydrochloric Acid SCHEMBL7943137 | 0.96 | GPR3 (0.33) | TNKS2PBRM1GPR3HTR2A | |
| Hydrochloric Acid SCHEMBL3119418 | 0.84 | GPR3 (0.40) | TNKS2PBRM1GPR3HTR2A | |
| Hydrochloric Acid SCHEMBL3759506 | 0.77 | KDM4E (0.33) | — | |
| Hydrochloric Acid SCHEMBL7754629 | 0.77 | BCHE (0.35) | — | |
| Hydrochloric Acid SCHEMBL339001 | 0.77 | KDM4E (0.33) | — | |
| Hydrochloric Acid SCHEMBL7211638 | 0.74 | GPR3 (0.31) | GPR3 | |
| Hydrochloric Acid SCHEMBL6437753 | 0.74 | GPR3 (0.30) | GPR3HTR2A | |
| Hydrochloric Acid SCHEMBL7936166 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL7932902 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010041779-A1 | PROCESS FOR MANUFACTURING POLYETHYLENE WITH A FUNCTIONAL END GROUP IN THE PRESENCE OF METALLOCENE CATALYST | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2001-11-15 | — | — | US | disclosed |
| EP-0678530-B1 | Process for production of cyclic olefin copolymers and copolymers produced by said process | MITSUI CHEMICALS INC (JP) | 2001-07-25 | — | — | EP | disclosed |
| EP-0719803-B1 | Process for the production of cycloolefin random copolymer | MITSUI CHEMICALS INC (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-5650471-A | COPOLYMERIZING AN ALPHA-OLEFIN AND A CYCLOOLEFIN IN THE PRESENCE OF A CATALYST FORMED FROM A TRANSITION METAL COMPOUND AND AN ORGANIC ALUMINUM COMPOUND | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-22 | — | — | US | disclosed |
| US-5559199-A | MOLECULAR WEIGHT CONTROL | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0729983-A2 | Process for the production of cycloolefin random copolymer | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-04 | — | — | EP | disclosed |
| EP-0719803-A2 | Process for the production of cycloolefin random copolymer | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| EP-0678530-A1 | Process for production of cyclic olefin copolymers and copolymers produced by said process | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-25 | — | — | EP | disclosed |