Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ICMT | O60725 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764577 | 0.82 | BCHE (0.56) | MEN1KMT2AICMTALBEPHX1 | |
| SCHEMBL8565479 | 0.81 | EPHX1 (0.48) | MEN1KMT2AICMTALBEPHX1 | |
| SCHEMBL7764590 | 0.81 | MEN1 (0.58) | MEN1KMT2AEPHX1CNR2CNR1 | |
| SCHEMBL7566432 | 0.78 | EPHX1 (0.65) | MEN1KMT2AICMTALBEPHX1 | |
| SCHEMBL7769378 | 0.78 | EPHX1 (0.65) | MEN1KMT2AICMTALBEPHX1 | |
| SCHEMBL8022082 | 0.77 | EPHX1 (0.48) | MEN1KMT2AICMTALBEPHX1 | |
| SCHEMBL7764576 | 0.77 | EPHX1 (0.64) | MEN1KMT2AICMTALBEPHX1 | |
| SCHEMBL7568901 | 0.77 | EPHX1 (0.64) | MEN1KMT2AICMTALBEPHX1 | |
| SCHEMBL7568943 | 0.75 | EPHX2 (0.64) | MEN1KMT2AICMTALBEPHX1 | |
| SCHEMBL7764597 | 0.72 | MEN1 (0.60) | MEN1KMT2ACNR2CNR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929515-B1 | NOVEL PHENOXYETHYLAMINE DERIVATIVES, METHOD OF PREPARATION, APPLICATION AS MEDICINE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CONSEILS DE RECH S SOC D (FR) | 2001-06-20 | — | — | EP | disclosed |
| US-6150417-A | ADMINISTERING TO WARM BLOODED ANIMALS COMPOUNDS SUCH AS N-TERT-BUTYL-5-((2-(2-METHOXYPHENOXY)ETHYL)AMINO)PENTANAMIDE FOR INDUCING ANTIEMETIC ACTIVITY; TREATING ANXIETY, DEPRESSION, AND SLEEP DISORDERS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (FR) | 2000-11-21 | — | — | US | disclosed |