Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | NPY2R | P49146 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963517 | 1.00 | ELANE (0.40) | ELANEKDM4EALDH1A1NPY2RL3MBTL1 | |
| SCHEMBL5964258 | 0.88 | ELANE (0.43) | ELANEALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL28495663 | 0.83 | ELANE (0.49) | ELANEKDM4EGAASMN1; SMN2MEN1 | |
| SCHEMBL7772609 | 0.82 | ELANE (0.47) | ELANEKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL5964086 | 0.82 | ELANE (0.49) | ELANEKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7778743 | 0.81 | ELANE (0.45) | ELANEKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7729786 | 0.81 | ELANE (0.47) | ELANEKDM4EALDH1A1HPGDGAA | |
| SCHEMBL5963742 | 0.80 | ELANE (0.44) | ELANEKDM4EALDH1A1HPGDGAA | |
| SCHEMBL5887440 | 0.80 | ELANE (0.46) | ELANEALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7732985 | 0.80 | ELANE (0.46) | ELANEKDM4EL3MBTL1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218553-B1 | METALLIZATION BY REACTING A BACCATIN III DERIVATIVE WITH A METAL ALKYLDISILAZIDE | THE STATE UNIVERSITY OF NEW YORK AT STONY BROOK | 2001-04-17 | — | — | US | disclosed |