Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.60 |
| ▸ | CA4 | P22748 | 1/20 | 0.60 |
| ▸ | CA6 | P23280 | 1/20 | 0.60 |
| ▸ | CA7 | P43166 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL3184806 | 0.91 | PKM (0.61) | ALDH1A1RECQLHPGDKDM4ESMN1; SMN2 | |
| Phthalic Acid SCHEMBL14976724 | 0.90 | ALDH1A1 (0.73) | ALDH1A1RECQLHPGDKDM4ESMN1; SMN2 | |
| Salicylic Acid SCHEMBL8595154 | 0.88 | ALDH1A1 (0.49) | ALDH1A1RECQLHPGDKDM4ESMN1; SMN2 | |
| Salicylic Acid SCHEMBL6063100 | 0.84 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL29099357 | 0.84 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL6062604 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL11308635 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Tetraethylene Glycol SCHEMBL6061658 | 0.83 | ALDH1A1 (0.64) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL6063018 | 0.82 | KDM4E (0.82) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 | |
| Salicylic Acid SCHEMBL290828 | 0.82 | KDM4E (0.82) | ALDH1A1HPGDKDM4ESMN1; SMN2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106163617-A | Composition for skin comprising queen bee venom | D·米切尔 | 2016-11-23 | — | — | CN | disclosed |
| EP-0763579-B1 | Bleed alleviated aqueous pigment dispersion-based ink-jet ink compositions | HEWLETT PACKARD CO (US) | 2001-07-11 | — | — | EP | disclosed |
| EP-0839881-A2 | Bleed alleviated aqueous pigment dispersion-based ink-jet ink compositions | Hewlett-Packard Company (US) | 1998-05-06 | — | — | EP | disclosed |
| US-5713989-A | Bleed alleviated aqueous pigment dispersion-based ink-jet ink compositions | HEWLETT-PACKARD COMPANY (US) | 1998-02-03 | — | — | US | disclosed |
| EP-0763578-A1 | Bleed-alleviated, waterfast, pigment-based, ink-jet ink compositions | Hewlett-Packard Company (US) | 1997-03-19 | — | — | EP | disclosed |
| EP-0763579-A1 | Bleed alleviated aqueous pigment dispersion-based ink-jet ink compositions | Hewlett-Packard Company (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5531816-A | Bleed-alleviated, waterfast, pigment-based ink-jet ink compositions | HEWLETT-PACKARD COMPANY (US) | 1996-07-02 | — | — | US | disclosed |