SCHEMBL7772867

SCHEMBL7772867

Oc1c(I)cc(CI)c2cccnc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.68
HSP90AA1 P07900 5/20 0.68
HTT P42858 5/20 0.68
SMN1; SMN2 Q16637 5/20 0.68
LMNA P02545 5/20 0.68
TP53 P04637 5/20 0.68
MEN1 O00255 5/20 0.68
KMT2A Q03164 5/20 0.68
ALDH1A1 P00352 5/20 0.68
TDP1 Q9NUW8 4/20 0.68
ALOX15 P16050 3/20 0.68
SLC6A2 P23975 3/20 0.68
USP2 O75604 3/20 0.68
HIF1A Q16665 3/20 0.68
HPGD P15428 2/20 0.68
MAPK1 P28482 2/20 0.68
PAX8 Q06710 2/20 0.68
HSD17B10 Q99714 2/20 0.68
EGFR P00533 1/20 0.68
ERBB2 P04626 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodoquinol SCHEMBL29606817 0.81 KDM4E (1.00) KDM4EHSP90AA1HTTSMN1; SMN2LMNA
Iodoquinol SCHEMBL29367180 0.81 KDM4E (1.00) KDM4EHSP90AA1HTTSMN1; SMN2LMNA
Iodoquinol SCHEMBL3460 0.81 KDM4E (1.00) KDM4EHSP90AA1HTTSMN1; SMN2LMNA
Iodoquinol SCHEMBL2532141 0.80 KDM4E (0.96) KDM4EHSP90AA1HTTSMN1; SMN2LMNA
SCHEMBL29154096 0.80 KDM4E (0.77) KDM4EHSP90AA1HTTSMN1; SMN2LMNA
Iodoquinol SCHEMBL28536045 0.80 KDM4E (0.96) KDM4EHSP90AA1HTTSMN1; SMN2LMNA
Iodoquinol SCHEMBL28518289 0.80 KDM4E (0.96) KDM4EHSP90AA1HTTSMN1; SMN2LMNA
Iodoquinol SCHEMBL28519246 0.80 KDM4E (0.96) KDM4EHSP90AA1HTTSMN1; SMN2LMNA
Clioquinol SCHEMBL11749381 0.77 KDM4E (1.00) KDM4EHSP90AA1HTTSMN1; SMN2LMNA
Clioquinol SCHEMBL3967 0.77 KDM4E (1.00) KDM4EHSP90AA1HTTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0731379-B1 Photographic emulsions containing tabular grains with a band structure and a central grain portion of high bromide concentration EASTMAN KODAK CO (US) 2001-10-04 EP disclosed
EP-0732617-B1 Photographic emulsions containing tabular grains with a band structure and a central grain portion of high chloride concentration EASTMAN KODAK CO (US) 2001-08-08 EP disclosed
EP-0731378-B1 Emulsions with tabular grain major faces formed by regions of differing iodide concentrations EASTMAN KODAK CO (US) 1999-06-30 EP disclosed
EP-0706079-B1 Grain growth process for the preparation of high bromide ultrathin tabular grain emulsions EASTMAN KODAK CO (US) 1997-07-30 EP disclosed
US-5558982-A High chloride (100) tabular grain emulsions with modified edge structures EASTMAN KODAK COMPANY (US) 1996-09-24 US disclosed
EP-0732617-A1 Photographic emulsions containing tabular grains with a band structure and a central grain portion of high chloride concentration EASTMAN KODAK COMPANY (US) 1996-09-18 EP disclosed
EP-0731378-A1 Emulsions with tabular grain major faces formed by regions of differing iodide concentrations EASTMAN KODAK COMPANY (US) 1996-09-11 EP disclosed
EP-0731379-A1 Photographic emulsions containing tabular grains with a band structure and a central grain portion of high bromide concentration EASTMAN KODAK COMPANY (US) 1996-09-11 EP disclosed
US-5512427-A SILVER HALIDE EMULSION WITH FACE-CENTERED CUBIC CRYSTAL LATTICE STRUCTURE HAVING PARALLEL MAJOR FACES AND AVERAGE ASPECT RATIO OF AT LEAST 5 EASTMAN KODAK COMPANY (US) 1996-04-30 US disclosed
US-5508160-A RADIATION-SENSITIVE; CONTAINS A 4,5,6-TRIAMINOPYRIMIDINE, A POLYIODOPHENOL OR AN IODO-8-HYDROXYQUINOLINE GRAIN GROWTH MODIFIER EASTMAN KODAK COMPANY (US) 1996-04-16 US disclosed
EP-0706079-A1 Grain growth process for the preparation of high bromide ultrathin tabular grain emulsions EASTMAN KODAK COMPANY (US) 1996-04-10 EP disclosed
EP-0694810-A1 A novel class of grain growth modifiers for the preparation of high chloride (111) Tabular grain emulsions (I) EASTMAN KODAK COMPANY (US) 1996-01-31 EP disclosed
EP-0670514-A2 High chloride (100) tabular grain emulsions with modified edge structures EASTMAN KODAK COMPANY (US) 1995-09-06 EP disclosed