Iodoquinol

Iodoquinol

SCHEMBL29367180

Oc1c(I)cc(I)c2cccnc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 1.00
MEN1 O00255 8/20 1.00
KMT2A Q03164 8/20 1.00
TDP1 Q9NUW8 7/20 1.00
HSP90AA1 P07900 6/20 1.00
HTT P42858 6/20 1.00
SMN1; SMN2 Q16637 6/20 1.00
ALDH1A1 P00352 6/20 1.00
LMNA P02545 5/20 1.00
TP53 P04637 4/20 1.00
USP2 O75604 3/20 1.00
ALOX15 P16050 3/20 1.00
SLC6A2 P23975 3/20 1.00
HPGD P15428 2/20 1.00
MAPK1 P28482 2/20 1.00
HIF1A Q16665 2/20 1.00
EGFR P00533 1/20 1.00
ERBB2 P04626 1/20 1.00
LCK P06239 1/20 1.00
FYN P06241 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodoquinol SCHEMBL29606817 1.00 KDM4E (1.00) KDM4EMEN1KMT2ATDP1HSP90AA1
Iodoquinol SCHEMBL3460 1.00 KDM4E (1.00) KDM4EMEN1KMT2ATDP1HSP90AA1
Iodoquinol SCHEMBL2532141 0.98 KDM4E (0.96) KDM4EMEN1KMT2ATDP1HSP90AA1
Iodoquinol SCHEMBL28519246 0.98 KDM4E (0.96) KDM4EMEN1KMT2ATDP1HSP90AA1
Iodoquinol SCHEMBL28536045 0.98 KDM4E (0.96) KDM4EMEN1KMT2ATDP1HSP90AA1
Iodoquinol SCHEMBL28518289 0.98 KDM4E (0.96) KDM4EMEN1KMT2ATDP1HSP90AA1
Chloroxine SCHEMBL29157288 0.87 KDM4E (0.80) KDM4EMEN1KMT2ATDP1HSP90AA1
Iodoquinol SCHEMBL7520643 0.87 KDM4E (0.77) KDM4EMEN1KMT2ATDP1HSP90AA1
SCHEMBL29154096 0.87 KDM4E (0.77) KDM4EMEN1KMT2ATDP1HSP90AA1
SCHEMBL4467681 0.84 KDM4E (0.72) KDM4EMEN1KMT2ATDP1HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116782865-A Atomic layer deposition coated pharmaceutical packages, improved syringes and vials, e.g., for lyophilization/cold chain drugs/vaccines SIO2医药产品公司 2023-09-19 CN claimed
CN-119731370-A Method and system for coating a drug container, cleaning a drug container and checking a drug container for particles and defects 二氧化硅医疗产品公司 2025-03-28 CN disclosed
CN-117750990-A Atomic layer deposition coated pharmaceutical packages and improved syringes and vials, e.g., for lyophilization/cold chain drugs/vaccines 二氧化硅医疗产品公司 2024-03-22 CN disclosed
US-20240066022-A1 DIIODOHYDROXYQUINOLINE FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE INFECTION PURDUE RESEARCH FOUNDATION (US) 2024-02-29 US disclosed
US-20240066022-A1 DIIODOHYDROXYQUINOLINE FOR THE TREATMENT OF CLOSTRIDIUM DIFFICILE INFECTION PURDUE RESEARCH FOUNDATION (US) 2024-02-29 US disclosed
US-11806342-B2 Diiodohydroxyquinoline for the treatment of clostridium difficile infection PURDUE RESEARCH FOUNDATION (US) 2023-11-07 US disclosed
CN-116782865-A Atomic layer deposition coated pharmaceutical packages, improved syringes and vials, e.g., for lyophilization/cold chain drugs/vaccines SIO2医药产品公司 2023-09-19 CN disclosed
CN-116547409-A Pulsed plasma enhanced chemical vapor deposition method and system SIO2医药产品公司 2023-08-04 CN disclosed
CN-116235052-A Methods for treating rheumatoid arthritis cardiovascular disease 美国实验室控股公司 2023-06-06 CN disclosed
CN-108474752-B System and method for detecting syringe seal defects W.L.戈尔及同仁股份有限公司 2022-02-01 CN disclosed