Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | MEN1 | O00255 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 1.00 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 6/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | TP53 | P04637 | 4/20 | 1.00 |
| ▸ | USP2 | O75604 | 3/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 2/20 | 1.00 |
| ▸ | EGFR | P00533 | 1/20 | 1.00 |
| ▸ | ERBB2 | P04626 | 1/20 | 1.00 |
| ▸ | LCK | P06239 | 1/20 | 1.00 |
| ▸ | FYN | P06241 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodoquinol SCHEMBL29367180 | 1.00 | KDM4E (1.00) | KDM4EMEN1KMT2ATDP1HSP90AA1 | |
| Iodoquinol SCHEMBL29606817 | 1.00 | KDM4E (1.00) | KDM4EMEN1KMT2ATDP1HSP90AA1 | |
| Iodoquinol SCHEMBL2532141 | 0.98 | KDM4E (0.96) | KDM4EMEN1KMT2ATDP1HSP90AA1 | |
| Iodoquinol SCHEMBL28519246 | 0.98 | KDM4E (0.96) | KDM4EMEN1KMT2ATDP1HSP90AA1 | |
| Iodoquinol SCHEMBL28536045 | 0.98 | KDM4E (0.96) | KDM4EMEN1KMT2ATDP1HSP90AA1 | |
| Iodoquinol SCHEMBL28518289 | 0.98 | KDM4E (0.96) | KDM4EMEN1KMT2ATDP1HSP90AA1 | |
| Chloroxine SCHEMBL29157288 | 0.87 | KDM4E (0.80) | KDM4EMEN1KMT2ATDP1HSP90AA1 | |
| Iodoquinol SCHEMBL7520643 | 0.87 | KDM4E (0.77) | KDM4EMEN1KMT2ATDP1HSP90AA1 | |
| SCHEMBL29154096 | 0.87 | KDM4E (0.77) | KDM4EMEN1KMT2ATDP1HSP90AA1 | |
| SCHEMBL4467681 | 0.84 | KDM4E (0.72) | KDM4EMEN1KMT2ATDP1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4961 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250248988-A1 | COMBINATION USES OF NITROXOLINE AND ITS ANALOGUES WITH CHEMOTHERAPIES AND IMMUNOTHERAPIES IN THE TREATMENT OF CANCERS | JIANGSU YAHONG MEDITECH CO., LTD. (CN) | 2025-08-07 | — | — | US | claimed |
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| US-12310960-B2 | Combinational uses of nitroxoline and its analogues with chemotherapies and immunotherapies in the treatment of cancers | JIANGSU YAHONG MEDITECH CO., LTD. (CN) | 2025-05-27 | — | — | US | claimed |
| WO-2025080590-A1 | CO-CRYSTALLIZATION OF ACTIVES WITH SACCHARIDE-BASED MOLECULAR FRAMEWORKS | SCIENTIFIC HORIZONS CONSULTING LLC (US) | 2025-04-17 | — | — | WO | claimed |
| US-12274830-B2 | Nitric oxide inhalation therapy for infants with bronchiolitis | BEYOND AIR LTD (IL) | 2025-04-15 | — | — | US | claimed |
| US-12171754-B2 | Combinational uses of nitroxoline and its analogues with chemotherapies and immunotherapies in the treatment of cancers | JIANGSU YAHONG MEDITECH CO., LTD. (CN) | 2024-12-24 | — | — | US | claimed |
| US-20240228912-A9 | COMPOSITION FOR CLEANING SEMICONDUCTOR SUBSTRATE, AND CLEANING METHOD | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-07-11 | — | — | US | claimed |
| US-20240173512-A1 | METHODS FOR POTENTIATING ANTIMICROBIAL AGENTS | STREETERVILLE CAPITAL, LLC | 2024-05-30 | — | — | US | claimed |
| CN-118084897-A | Iron ion detection reagent and preparation method and application thereof | 河南省氟基新材料科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| US-20240132805-A1 | COMPOSITION FOR CLEANING SEMICONDUCTOR SUBSTRATE, AND CLEANING METHOD | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2024-04-25 | — | — | US | claimed |
| EP-0037175-B1 | PHARMACEUTICAL COMPOSITIONS | EFAMOL LIMITED (GB) | 1988-02-10 | — | — | EP | claimed |
| EP-0096457-B1 | INDIUM COMPLEXES OF SUBSTITUTED 8-HYDROXY-QUINOLINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS ANTIBACTERIAL AGENTS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-03-11 | — | — | EP | claimed |
| EP-0046270-B1 | NOVEL DERIVATIVES OF BIO-AFFECTING PHENOLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | INTERx RESEARCH CORPORATION (US) | 1986-05-21 | — | — | EP | claimed |
| US-4560553-A | THERAPEUTIC, COSMETIC;MIXTURES OF HYPOTENSIVES, ANESTHETICS, BETA-BLOCKERS AND MICROBIOCIDES | MERCK & CO., INC. (US) | 1985-12-24 | — | — | US | claimed |
| EP-0035856-B1 | PHARMACEUTICAL AND DIETARY COMPOSITIONS | EFAMOL LIMITED (GB) | 1984-07-04 | — | — | EP | claimed |
| EP-0096457-A1 | Indium complexes of substituted 8-hydroxy-quinolines, pharmaceutical compositions containing them and their use as antibacterial agents | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-12-21 | — | — | EP | claimed |
| US-RE31463-E | TECHNETIUM, COBALT, GALLIUM, INDIUM AND SUBSTITUTED IMINODIACETIC ACID | RESEARCH CORPORATION (US) | 1983-12-13 | — | — | US | claimed |
| EP-0046270-A1 | Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them | INTERx RESEARCH CORPORATION (US) | 1982-02-24 | — | — | EP | claimed |
| US-4312855-A | FOR IMPROVING DEPOSITION OR RETENTION OF ACTIVE MATERIAL; HAIR CONDITIONERS, DETERGENTS | COLGATE-PALMOLIVE COMPANY (US) | 1982-01-26 | — | — | US | claimed |
| EP-0035856-A2 | Pharmaceutical and dietary compositions | EFAMOL LIMITED (GB) | 1981-09-16 | — | — | EP | claimed |