Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134916 | 0.92 | TSHR (0.47) | TSHRALDH1A1TGFBR1 | |
| SCHEMBL28479817 | 0.83 | TSHR (0.43) | TSHRALDH1A1TGFBR1 | |
| SCHEMBL27547001 | 0.82 | PAOX (0.37) | TSHRALDH1A1 | |
| SCHEMBL28108398 | 0.80 | TSHR (0.35) | TSHRALDH1A1 | |
| SCHEMBL2346839 | 0.76 | ALDH1A1 (0.40) | TSHRALDH1A1TGFBR1TDP1 | |
| SCHEMBL867377 | 0.76 | TSHR (0.46) | TSHRALDH1A1TGFBR1 | |
| SCHEMBL5569319 | 0.76 | TDP1 (0.40) | TSHRALDH1A1TGFBR1TDP1 | |
| SCHEMBL11024824 | 0.75 | TSHR (0.36) | TSHR | |
| SCHEMBL7601590 | 0.75 | TSHR (0.36) | TSHRALDH1A1TGFBR1TDP1 | |
| SCHEMBL10947111 | 0.75 | TSHR (0.43) | TSHRALDH1A1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121623-A1 | IONIZATION RADIATION IMAGEABLE PHOTOPOLYMER COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000020926-A1 | IONIZATION RADIATION IMAGEABLE PHOTOPOLYMER COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-04-13 | — | — | WO | disclosed |