Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27554254 | 0.98 | ABCC4 (0.50) | ABCC4MAPTLMNAFFAR4FFAR1 | |
| SCHEMBL23576313 | 0.94 | TSHR (0.47) | ABCC4MAPTLMNAFFAR4TSHR | |
| SCHEMBL15026862 | 0.85 | — | — | |
| Adipic Acid SCHEMBL3419725 | 0.83 | AKR1B1 (0.48) | ABCC4MAPTLMNAFFAR4FFAR1 | |
| SCHEMBL27612561 | 0.81 | GSTK1 (0.50) | LMNAFFAR4FFAR1TSHRNFKB1 | |
| SCHEMBL5712957 | 0.79 | GSTK1 (0.52) | LMNAFFAR4FFAR1TSHRNFKB1 | |
| SCHEMBL17062972 | 0.79 | GSTK1 (0.52) | LMNAFFAR4FFAR1TSHRNFKB1 | |
| Propene SCHEMBL29115863 | 0.79 | KDM4C (0.51) | ABCC4MAPTLMNAFFAR4FFAR1 | |
| SCHEMBL17062999 | 0.79 | GSTK1 (0.52) | LMNAFFAR4FFAR1TSHRNFKB1 | |
| SCHEMBL6287572 | 0.78 | LMNA (0.50) | ABCC4MAPTLMNAFFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160075732-A1 | RADICAL ORBITAL SWITCHING | THE AUSTRALIAN NATIONAL UNIVERSITY (AU) | 2016-03-17 | — | — | US | disclosed |
| WO-2001053249-A1 | PROCESS FOR THE CARBONYLATION OF BUTADIENE AND/OR AT LEAST ONE BUTADIENE DERIVATIVE | DSM N.V. (NL) | 2001-07-26 | — | — | WO | disclosed |
| EP-1118607-A1 | Process for the carbonylation of butadiene and/or at least one butadiene derivative | DSM N.V. (NL) | 2001-07-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160075732-A1 | RADICAL ORBITAL SWITCHING | RAD1, RAD54L, NQO1 | ABCC4 3727/4885MAPT 3061/4885LMNA 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.