Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.47 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10404891 | 0.98 | ABCC4 (0.54) | LMNAABCC4MAPTFFAR4FFAR1 | |
| SCHEMBL10280473 | 0.98 | ABCC4 (0.54) | LMNAABCC4MAPTFFAR4FFAR1 | |
| SCHEMBL7113665 | 0.98 | ABCC4 (0.54) | LMNAABCC4MAPTFFAR4FFAR1 | |
| SCHEMBL30969111 | 0.93 | NFKB1 (0.50) | LMNAABCC4MAPTTSHRNFKB1 | |
| SCHEMBL14883227 | 0.89 | FFAR1 (0.56) | LMNAABCC4MAPTFFAR4FFAR1 | |
| Dimethylamine SCHEMBL28092926 | 0.85 | NFKB1 (0.44) | LMNAABCC4MAPTFFAR4FFAR1 | |
| SCHEMBL28623051 | 0.83 | — | — | |
| SCHEMBL5437330 | 0.83 | TRPA1 (0.34) | MAPTTSHRNFKB1SLC6A2SLC6A4 | |
| SCHEMBL8994356 | 0.82 | GSTK1 (0.36) | ABCC4MAPTFFAR4FFAR1TSHR | |
| Propylamine SCHEMBL28093163 | 0.81 | FFAR4 (0.44) | LMNAMAPTFFAR4FFAR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078215-A1 | SIGMATROPIC REARRANGEMENTS OF POLYMER BACKBONES | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2026-03-19 | — | — | US | disclosed |
| US-12503550-B2 | Sigmatropic rearrangements of polymer backbones | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2025-12-23 | — | — | US | disclosed |
| US-20250002644-A1 | SIGMATROPIC REARRANGEMENTS OF POLYMER BACKBONES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2025-01-02 | — | — | US | disclosed |
| WO-2023086289-A1 | SIGMATROPIC REARRANGEMENTS OF POLYMER BACKBONES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-05-19 | — | — | WO | disclosed |
| US-6864287-B1 | Derivatives of dicarboxylic acid having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260078215-A1 | SIGMATROPIC REARRANGEMENTS OF POLYMER BACKBONES | SIGMAR1, TRRAP, PIK3R4 | LMNA 3528/4885ABCC4 447/4885MAPT 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.