Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775266 | 0.85 | NPC1 (0.52) | NPC1SIGMAR1POLB | |
| SCHEMBL20257439 | 0.84 | HTT (0.48) | NPC1HTTTGM2SMN1; SMN2 | |
| SCHEMBL7775260 | 0.84 | NPC1 (0.51) | NPC1SIGMAR1POLB | |
| SCHEMBL7773267 | 0.82 | NPC1 (0.55) | NPC1HTTALDH1A1SIGMAR1POLB | |
| SCHEMBL13177104 | 0.81 | HTT (0.49) | NPC1HTTL3MBTL1TGM2SMN1; SMN2 | |
| SCHEMBL7769141 | 0.80 | CYP2C19 (0.49) | HTTTGM2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7773263 | 0.80 | NPC1 (0.56) | NPC1L3MBTL1SIGMAR1POLB | |
| SCHEMBL7776781 | 0.80 | ALDH1A1 (0.48) | NPC1L3MBTL1ALDH1A1SMN1; SMN2SIGMAR1 | |
| SCHEMBL8861893 | 0.77 | HTT (0.54) | HTTTGM2ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7773290 | 0.77 | SIGMAR1 (0.49) | L3MBTL1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517325-B1 | Drug hapten analogues for immunoassays | JOHNSON & JOHNSON CLIN DIAG (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-0517327-B1 | Immunoassay with labeled hapten analogues | JOHNSON & JOHNSON CLIN DIAG (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0517326-B1 | Labeled drug hapten analogues for immunoassays | JOHNSON & JOHNSON CLIN DIAG (US) | 2001-08-16 | — | — | EP | disclosed |
| US-5601994-A | Immunoassay with novel labeled drug hapten analogues | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| US-5298403-A | Having hydantoin or barbiturate nucleus | EASTMAN KODAK COMPANY (US) | 1994-03-29 | — | — | US | disclosed |
| US-5284948-A | Drug hapten analogues for immunoassays | EASTMAN KODAK COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0517326-A2 | Labeled drug hapten analogues for immunoassays | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-12-09 | — | — | EP | disclosed |
| EP-0517327-A2 | Immunoassay with labeled hapten analogues | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-12-09 | — | — | EP | disclosed |
| EP-0517325-A2 | Drug hapten analogues for immunoassays | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-12-09 | — | — | EP | disclosed |