Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769118 | 0.88 | NPC1 (0.50) | NPC1POLBL3MBTL1SIGMAR1HRH1 | |
| SCHEMBL7775266 | 0.88 | NPC1 (0.52) | NPC1POLBSIGMAR1HRH1HRH3 | |
| SCHEMBL7769115 | 0.86 | NPC1 (0.48) | NPC1POLBL3MBTL1SIGMAR1HRH1 | |
| SCHEMBL7773267 | 0.84 | NPC1 (0.55) | NPC1POLBSIGMAR1HRH1HRH3 | |
| SCHEMBL7769114 | 0.82 | CYP2C19 (0.46) | NPC1 | |
| SCHEMBL7776766 | 0.81 | HRH1 (0.60) | POLBSIGMAR1HRH1HRH3TDP1 | |
| SCHEMBL7775260 | 0.81 | NPC1 (0.51) | NPC1POLBSIGMAR1HRH1HRH3 | |
| SCHEMBL7904117 | 0.80 | SIGMAR1 (0.60) | POLBSIGMAR1HRH1HRH3TDP1 | |
| SCHEMBL7773254 | 0.80 | NPC1 (0.48) | NPC1POLBL3MBTL1SIGMAR1 | |
| SCHEMBL9697267 | 0.78 | POLB (0.56) | NPC1POLBSIGMAR1HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517325-B1 | Drug hapten analogues for immunoassays | JOHNSON & JOHNSON CLIN DIAG (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-0517326-B1 | Labeled drug hapten analogues for immunoassays | JOHNSON & JOHNSON CLIN DIAG (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-0517327-B1 | Immunoassay with labeled hapten analogues | JOHNSON & JOHNSON CLIN DIAG (US) | 2001-08-16 | — | — | EP | disclosed |
| US-5601994-A | Immunoassay with novel labeled drug hapten analogues | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| US-5298403-A | Having hydantoin or barbiturate nucleus | EASTMAN KODAK COMPANY (US) | 1994-03-29 | — | — | US | disclosed |
| US-5284948-A | Drug hapten analogues for immunoassays | EASTMAN KODAK COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| EP-0517326-A2 | Labeled drug hapten analogues for immunoassays | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-12-09 | — | — | EP | disclosed |
| EP-0517327-A2 | Immunoassay with labeled hapten analogues | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-12-09 | — | — | EP | disclosed |
| EP-0517325-A2 | Drug hapten analogues for immunoassays | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-12-09 | — | — | EP | disclosed |