SCHEMBL77733

SCHEMBL77733

COC(=O)C=C(C(=O)OC)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
KDM4E B2RXH2 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 4/20 0.42
HPGD P15428 1/20 0.42
HTT P42858 1/20 0.42
MAPT P10636 3/20 0.41
LMNA P02545 2/20 0.41
GAA P10253 1/20 0.41
SRC P12931 1/20 0.41
AKR1C1 Q04828 1/20 0.40
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
RECQL P46063 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3681269 1.00 TSHR (0.48) TSHRKDM4ESMN1; SMN2TDP1L3MBTL1
SCHEMBL6394005 1.00 TSHR (0.48) TSHRKDM4ESMN1; SMN2TDP1L3MBTL1
SCHEMBL12268119 0.87 AKR1C1 (0.50) TSHRKDM4EALDH1A1HPGDHTT
SCHEMBL4007052 0.87 TSHR (0.50) TSHRKDM4ESMN1; SMN2TDP1L3MBTL1
SCHEMBL4007049 0.87 TSHR (0.50) TSHRKDM4ESMN1; SMN2TDP1L3MBTL1
SCHEMBL10353495 0.85 ALDH1A1 (0.53) TSHRKDM4ESMN1; SMN2ALDH1A1HPGD
SCHEMBL28099697 0.85 TSHR (0.48) TSHRKDM4EALDH1A1HPGDHTT
SCHEMBL4732473 0.85 NFE2L2 (0.52) TSHRKDM4ESMN1; SMN2TDP1L3MBTL1
Methane SCHEMBL534895 0.85 TSHR (0.48) TSHRKDM4ESMN1; SMN2TDP1L3MBTL1
SCHEMBL9726821 0.85 MAPT (0.47) TSHRKDM4ESMN1; SMN2TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3926 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1582549-B1 Flame retardant resin blends based on polymers derived from 2-hydrocarbyl-3,3-Bis(4-Hydroxyaryl)Phthalimidine monomers SABIC INNOVATIVE PLASTICS IP (NL) 2011-03-09 EP claimed
US-6391949-B1 None US disclosed
EP-4747310-A1 NON-FLUORINATED POLYMER PROCESSING AIDS FOR DIE LIP BUILD-UP MITIGATION IN EXTRUSION OF COMPOSITIONS CONTAINING RECYCLED POLYETHYLENE Nova Chemicals (International) S.A. (CH) 2026-05-27 EP disclosed
EP-4536463-B1 PROCESS TO PREPARE THERMOPLASTIC COMPOSITIONS COMPRISING FLUORINE FREE POLYMER PROCESSING AIDS NOVA CHEMICALS INTERNATIONAL SA (CH) 2026-05-13 EP disclosed
EP-4731727-A1 HALF-WAVE PLATE Merck Patent GmbH (DE) 2026-04-29 EP disclosed
EP-4731708-A1 POLAR POLYMERS AS PROCESSING AIDS IN POLYETHYLENE Nova Chemicals (International) S.A. (CH) 2026-04-29 EP disclosed
EP-4728007-A1 NON-FLUORINATED POLYMER PROCESS AIDS Nova Chemicals (International) S.A. (CH) 2026-04-22 EP disclosed
EP-4713414-A1 OPTICAL ELEMENT COMPRISING A CHIRAL LC POLYMER FILM Merck Patent GmbH (DE) 2026-03-25 EP disclosed
EP-4713413-A1 CHIRAL REACTIVE MESOGEN MIXTURE Merck Patent GmbH (DE) 2026-03-25 EP disclosed
EP-4689004-A1 CHIRAL REACTIVE MESOGEN MIXTURE Merck Patent GmbH (DE) 2026-02-11 EP disclosed
US-3956427-A STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-05-11 US disclosed
US-3954839-A LIGHT AND HEAT STABILIZERS FOR POLYOLEFINS CIBA-GEIGY CORPORATION (US) 1976-05-04 US disclosed
US-3954708-A Synthetic polymers stabilized with a nickel benzoate and a polyol CIBA-GEIGY CORPORATION (US) 1976-05-04 US disclosed
US-3948854-A Salicylic acid hydrazide stabilizers for polymers CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed
US-3948852-A Nickel stabilisers for synthetic polymers CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed
US-3944632-A Phosphoric acid anilides CIBA-GEIGY CORPORATION (US) 1976-03-16 US disclosed
US-3943096-A Use of hydroxyphenylurethanes for stabilising elastomers CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed
US-3943098-A 1-Aza-4-thiacyclohexane-4,4-dioxide derivatives and their use as agents protecting against light rays CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed
US-3943106-A POLYESTERS AND POLYAMIDS FROM HYDROXYBENZYLMALONIC ACID DERIVATIVES; STABILIZERS CIBA-GEIGY CORPORATION (US) 1976-03-09 US disclosed
US-3939175-A STABILIZER CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed