Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971360 | 0.95 | ATM (0.41) | ELANEATML3MBTL1TDP1ZDHHC7 | |
| SCHEMBL7062133 | 0.88 | ATM (0.44) | ELANEATML3MBTL1TDP1NSD2 | |
| SCHEMBL7773448 | 0.84 | ZDHHC7 (0.57) | TDP1ZDHHC7PRSS1PRSS2PRSS3 | |
| SCHEMBL27527798 | 0.84 | ZDHHC7 (0.47) | ATML3MBTL1TDP1ZDHHC7PRSS1 | |
| SCHEMBL8565502 | 0.82 | ALDH1A1 (0.46) | ATML3MBTL1TDP1ZDHHC7PRSS1 | |
| SCHEMBL9849997 | 0.81 | ATM (0.46) | ELANEATML3MBTL1TDP1NSD2 | |
| SCHEMBL9436169 | 0.81 | ZDHHC2 (0.61) | ZDHHC7PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL7973064 | 0.79 | TDP1 (0.49) | L3MBTL1TDP1HPGDALDH1A1 | |
| SCHEMBL7973118 | 0.77 | ESR1 (0.47) | L3MBTL1TDP1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL27506827 | 0.76 | L3MBTL1 (0.50) | ELANEATML3MBTL1PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |