Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771538 | 0.95 | HDAC1 (0.64) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL7773674 | 0.93 | HDAC1 (0.67) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL7770886 | 0.93 | HDAC1 (0.67) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL4854980 | 0.89 | HSD11B1 (0.65) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL5128861 | 0.85 | HDAC1 (0.60) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL2810870 | 0.83 | HDAC1 (0.58) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL5120938 | 0.83 | HDAC1 (0.58) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL11474890 | 0.82 | ALDH1A1 (0.67) | KMT2ARAB9AMAPT | |
| SCHEMBL1232793 | 0.81 | HDAC1 (0.57) | HDAC1HDAC8HDAC2HDAC3HDAC4 | |
| SCHEMBL6803062 | 0.81 | HDAC1 (0.57) | HDAC1HDAC8HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |
| EP-0007623-B1 | PROCESS FOR THE PREPARATION OF THERMOSTABLE N-ALKYL-ARYLSULPHONAMIDES AND THEIR USE AS PLASTICIZERS FOR POLYAMIDES | BASF Aktiengesellschaft (DE) | 1982-02-24 | — | — | EP | disclosed |
| EP-0007623-A1 | Process for the preparation of thermostable N-alkyl-arylsulphonamides and their use as plasticizers for polyamides | BASF Aktiengesellschaft (DE) | 1980-02-06 | — | — | EP | disclosed |