SCHEMBL7773643

SCHEMBL7773643

CCCc1cc(CCl)c2c(c1)OCO2

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.60
CYP3A4 P08684 3/20 0.60
SMN1; SMN2 Q16637 1/20 0.37
TAAR1 Q96RJ0 3/20 0.34
TSHR P16473 1/20 0.34
ALKBH5 Q6P6C2 1/20 0.33
DHFR P00374 1/20 0.33
HTR7 P34969 2/20 0.32
TRPV1 Q8NER1 1/20 0.32
CALM1 P0DP23 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26782451 0.75 CYP3A4 (1.00) ALDH1A1CYP3A4SMN1; SMN2ALKBH5HTR7
SCHEMBL9148130 0.73 CYP3A4 (0.53) ALDH1A1CYP3A4SMN1; SMN2TAAR1TSHR
SCHEMBL25844870 0.73 MAOB (0.34) ALDH1A1CYP3A4SMN1; SMN2
SCHEMBL26113185 0.72 ALDH1A1 (0.48) ALDH1A1CYP3A4TSHR
SCHEMBL25844872 0.72 ALDH1A1 (0.36) ALDH1A1CYP3A4SMN1; SMN2MEN1KMT2A
SCHEMBL26115179 0.71 ALDH1A1 (0.47) ALDH1A1CYP3A4
SCHEMBL429483 0.69 TAAR1 (0.67) ALDH1A1CYP3A4TAAR1CALM1SLC6A2
SCHEMBL29079404 0.69 CNR1 (0.41) ALDH1A1CYP3A4DHFR
Bromide SCHEMBL29260497 0.68 TAAR1 (0.65) ALDH1A1CYP3A4TAAR1CALM1SLC6A2
SCHEMBL1464593 0.68 CYP3A4 (0.39) ALDH1A1CYP3A4SMN1; SMN2TAAR1HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6320085-B1 REACTING BENZYL ALCOHOL DERIVATIVE WITH 1 TO 3 MOLAR EQUIVALENTS OF SPECIFIED ALCOHOL IN PRESENCE OF ACID, LEWIS ACID, METAL OXIDE OR METAL CARBONATE, ISOLATING RESULTING ETHER, STABILIZING BY ADDITION OF BASE AND/OR ANTIOXIDANT AGRO-CHEMIE NOVENYVEDOSZER GYARTO ERTEKESITO EST FORGALMAZO KFT. (HU) 2001-11-20 US disclosed
EP-0939749-B1 PROCESS FOR THE PREPARATION OF BENZYL-ETHERS AGRO CHEMIE NOEVENYVEDOESZER G (HU) 2001-07-18 EP disclosed
EP-0939749-A1 PROCESS FOR THE PREPARATION OF BENZYL-ETHERS Agro-Chemie Növenyvedöszer Gyárto Ertékesito Es Forgalmazo KFT. (HU) 1999-09-08 EP disclosed
WO-1998022417-A1 PROCESS FOR THE PREPARATION OF BENZYL-ETHERS BY USE OF PHASE TRANSFER Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) 1998-05-28 WO disclosed
WO-1998022416-A1 PROCESS FOR THE PREPARATION OF BENZYL-ETHERS AGRO-CHEMIE NÖVÉNYVÉDÖSZER GYÁRTÓ ÉRTÉKESITÓ ÉS FORGALMAZÓ KFT. (HU) 1998-05-28 WO disclosed