Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28400947 | 0.90 | CYP3A4 (0.65) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL28386231 | 0.90 | CYP3A4 (0.65) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL11575857 | 0.85 | ALOX5 (0.66) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL28378162 | 0.85 | ALOX5 (0.66) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL2683415 | 0.85 | ALOX5 (0.66) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL906528 | 0.84 | ALOX5 (0.67) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL5723843 | 0.82 | ALOX5 (0.66) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL28894778 | 0.79 | CYP3A4 (0.58) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL28894516 | 0.79 | CYP3A4 (0.58) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL7795393 | 0.79 | CYP3A4 (0.64) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115392-A2 | USE OF N-ACYLVANILLINAMIDE DERIVATIVES AS AGONISTS OF PERIPHERAL CANNABINOID CB1 RECEPTORS | Innovet Italia S.r.l. (IT) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000016756-A2 | USE OF N-ACYLVANILLINAMIDE DERIVATIVES AS AGONISTS OF PERIPHERAL CANNABINOID CB1 RECEPTORS | INNOVET ITALIA S.R.L. (IT) | 2000-03-30 | — | — | WO | disclosed |