Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11481778 | 0.99 | ALDH1A1 (0.47) | ALDH1A1MAPK1GAANPSR1HSP90AA1 | |
| SCHEMBL11481776 | 0.99 | ALDH1A1 (0.47) | ALDH1A1MAPK1GAANPSR1HSP90AA1 | |
| SCHEMBL7778947 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MAPK1GAANPSR1TDP1 | |
| SCHEMBL7782342 | 0.81 | NPC1 (0.47) | ALDH1A1MAPK1GAANPC1RAB9A | |
| SCHEMBL7782268 | 0.80 | NPC1 (0.62) | ALDH1A1MAPK1GAANPC1RAB9A | |
| SCHEMBL11485616 | 0.79 | RAB9A (0.49) | ALDH1A1MAPK1GAANPSR1HSP90AA1 | |
| SCHEMBL11485620 | 0.79 | RAB9A (0.49) | ALDH1A1MAPK1GAANPSR1HSP90AA1 | |
| SCHEMBL11472131 | 0.79 | NPC1 (0.65) | ALDH1A1MAPK1GAANPC1RAB9A | |
| SCHEMBL11472132 | 0.79 | NPC1 (0.65) | ALDH1A1MAPK1GAANPC1RAB9A | |
| SCHEMBL11369345 | 0.78 | PDE4A (0.44) | ALDH1A1MAPK1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949247-B1 | Process for the preparation of piperidinylidene derivatives | TAKASAGO PERFUMERY CO LTD (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-6008358-A | Process for the preparation of piperidinylidene derivative | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0949247-A1 | Process for the preparation of piperidinylidene derivatives | Takasago International Corporation (JP) | 1999-10-13 | — | — | EP | disclosed |