Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.42 |
| ▸ | F13A1 | P00488 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16116690 | 0.98 | TBXAS1 (0.45) | TBXAS1F13A1MAPTRXFP1PPARA | |
| SCHEMBL7186166 | 0.98 | TBXAS1 (0.45) | TBXAS1F13A1MAPTRXFP1PPARA | |
| SCHEMBL5818912 | 0.95 | SMN1; SMN2 (0.41) | TBXAS1F13A1MAPTRXFP1KDM4E | |
| SCHEMBL907879 | 0.87 | KDM4E (0.44) | KDM4ELMNAKDM4C | |
| SCHEMBL7782045 | 0.80 | HPGD (0.43) | MAPTLMNAKDM4CTSHR | |
| SCHEMBL19051554 | 0.80 | SMN1; SMN2 (0.48) | KDM4ELMNATSHR | |
| SCHEMBL25754985 | 0.79 | TBXAS1 (0.40) | TBXAS1KDM4C | |
| Oxalic Acid SCHEMBL27277082 | 0.77 | KDM4E (0.39) | MAPTKDM4ELMNAKDM4CTSHR | |
| SCHEMBL2098331 | 0.73 | SLC6A3 (0.33) | LMNATSHR | |
| SCHEMBL18531931 | 0.72 | KCNH2 (0.47) | TBXAS1KDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135377-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000034254-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2000-06-15 | — | — | WO | disclosed |