Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 4/20 | 0.49 |
| ▸ | PTPRG | P23470 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380082 | 0.81 | PTPRG (0.58) | CYP1A2IDO1PTPRGPTPRCMAPT | |
| SCHEMBL3241580 | 0.80 | MEN1 (0.50) | MAPTL3MBTL1MIFMEN1KMT2A | |
| SCHEMBL7779170 | 0.79 | MEN1 (0.67) | IDO1MAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL694407 | 0.79 | CYP1A2 (0.46) | CYP1A2IDO1PTPRGPTPRCMAPT | |
| SCHEMBL31395215 | 0.78 | ALDH1A1 (0.52) | CYP1A2IDO1PTPRGPTPRCMAPT | |
| SCHEMBL7782032 | 0.78 | MEN1 (0.46) | IDO1MAPTMIFMEN1KMT2A | |
| SCHEMBL31395362 | 0.76 | KMT2A (0.54) | CYP1A2PTPRGMAPTL3MBTL1MEN1 | |
| SCHEMBL4542980 | 0.75 | LTA4H (0.50) | HSD17B10HIF1AMIFMEN1KMT2A | |
| SCHEMBL11587862 | 0.75 | ESR1 (0.61) | IDO1HSD17B10MAPTMEN1KMT2A | |
| SCHEMBL27772541 | 0.75 | ESR1 (0.61) | IDO1HSD17B10L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135377-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000034254-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2000-06-15 | — | — | WO | disclosed |