Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | HPGD | P15428 | 8/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775208 | 0.89 | ALDH1A1 (0.41) | KMT2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL7775061 | 0.79 | CYP1A2 (0.37) | KMT2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL7770561 | 0.73 | KDM4E (0.45) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7770152 | 0.72 | KMT2A (0.36) | KMT2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL15558253 | 0.71 | L3MBTL1 (0.46) | KMT2AKDM4EALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL6507803 | 0.71 | ALDH1A1 (0.40) | KMT2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL7775207 | 0.70 | TNKS2 (0.36) | KMT2AKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7248441 | 0.69 | SMN1; SMN2 (0.38) | KMT2AKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL7248300 | 0.69 | PPARA (0.45) | KDM4EALDH1A1HPGDTHRB | |
| SCHEMBL6055987 | 0.69 | ALDH1A1 (0.47) | KMT2AALDH1A1TSHRSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1280574-A | Heterocyclic compounds, their use in medicine, processes for their preparation and pharmaceutical compositions containing them | REDDY CHEMINOR INC (IN) | 2001-01-17 | — | — | CN | claimed |
| EP-1124807-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2001-08-22 | — | — | EP | disclosed |
| CN-1280574-A | Heterocyclic compounds, their use in medicine, processes for their preparation and pharmaceutical compositions containing them | REDDY CHEMINOR INC (IN) | 2001-01-17 | — | — | CN | disclosed |
| WO-1999016758-A1 | NOVEL HETEROCYCLIC COMPOUNDS AND THEIR USE IN MEDICINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-04-08 | — | — | WO | disclosed |