Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 8/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509349 | 0.75 | TP53 (0.36) | ALDH1A1KDM4ESMN1; SMN2GAAKMT2A | |
| SCHEMBL6532064 | 0.72 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2GAAKMT2A | |
| SCHEMBL7775210 | 0.71 | KMT2A (0.43) | ALDH1A1KDM4ESMN1; SMN2GAAKMT2A | |
| SCHEMBL6532465 | 0.70 | MAPT (0.41) | ALDH1A1KMT2AHPGDTSHRTP53 | |
| SCHEMBL6508551 | 0.69 | KDM4E (0.44) | ALDH1A1KDM4ESMN1; SMN2GAAHPGD | |
| SCHEMBL7775208 | 0.67 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2GAAKMT2A | |
| SCHEMBL6505883 | 0.67 | MAPT (0.32) | HTT | |
| SCHEMBL14259786 | 0.65 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2GAAKMT2A | |
| SCHEMBL7775061 | 0.64 | CYP1A2 (0.37) | ALDH1A1KDM4ESMN1; SMN2GAAKMT2A | |
| SCHEMBL15558253 | 0.63 | L3MBTL1 (0.46) | ALDH1A1KDM4ESMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100318-A1 | ALKANOIC ACIDS AND THEIR ESTERS AS ANTIDIABETIC AGENTS | RANBAXY LABORATORIES LIMITED (US) | 2005-10-27 | — | — | WO | disclosed |