Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ELANE | P08246 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862275 | 0.90 | NPC1 (0.57) | NPC1MAPTRAB9APOLBELANE | |
| SCHEMBL9615830 | 0.84 | NPC1 (0.43) | NPC1MAPTRAB9APOLBELANE | |
| SCHEMBL7619158 | 0.84 | NPC1 (0.52) | NPC1MAPTRAB9APOLBKMT2A | |
| SCHEMBL8026374 | 0.84 | NPC1 (0.52) | NPC1MAPTRAB9APOLBKMT2A | |
| SCHEMBL7775226 | 0.80 | ELANE (0.51) | NPC1MAPTRAB9APOLBELANE | |
| SCHEMBL7862273 | 0.79 | NPC1 (0.51) | NPC1MAPTRAB9APOLBELANE | |
| SCHEMBL26866501 | 0.79 | ELANE (0.61) | NPC1MAPTRAB9APOLBELANE | |
| SCHEMBL23487602 | 0.78 | ELANE (0.78) | MAPTRAB9APOLBELANEKMT2A | |
| SCHEMBL7776919 | 0.78 | PARP10 (0.57) | NPC1MAPTRAB9APOLBKMT2A | |
| SCHEMBL7626930 | 0.78 | ADRB2 (0.48) | NPC1MAPTRAB9APOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300454-B1 | Liquid-crystalline nematic organosiloxanes which can be crosslinked to form optically anisotropic polymer layers | WACKER-CHEMIE GMBH (DE) | 2001-10-09 | — | — | US | disclosed |
| EP-0985721-B1 | Nematic liquid crystalline organosiloxanes crosslinkable to optical anisotropic polymer layers | CONSORTIUM ELEKTROCHEM IND (DE) | 2001-08-29 | — | — | EP | disclosed |
| EP-0985721-A1 | Nematic liquid crystalline organosiloxanes crosslinkable to optical anisotropic polymer layers | Consortium für elektrochemische Industrie GmbH (DE) | 2000-03-15 | — | — | EP | disclosed |