Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CTSE | P14091 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5890038 | 1.00 | LMNA (0.48) | LMNACCR5TAAR1POLBCYP2D6 | |
| SCHEMBL2240978 | 1.00 | LMNA (0.48) | LMNACCR5TAAR1POLBCYP2D6 | |
| SCHEMBL169508 | 0.85 | LMNA (0.56) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL9452584 | 0.85 | HTR2A (0.43) | LMNATAAR1CYP2D6TRPA1HTR2A | |
| Ammonia Solution, Strong SCHEMBL1640901 | 0.82 | LMNA (0.54) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL7986873 | 0.82 | AOC3 (0.43) | LMNACCR5TAAR1POLBSIGMAR1 | |
| SCHEMBL27493681 | 0.82 | LMNA (0.45) | LMNACCR5TAAR1CYP2D6CTSD | |
| SCHEMBL27710910 | 0.82 | LMNA (0.45) | LMNACCR5TAAR1CYP2D6CTSD | |
| SCHEMBL8097091 | 0.81 | LMNA (0.48) | LMNACCR5TAAR1CYP2D6MIF | |
| Methylamine SCHEMBL27931105 | 0.80 | LMNA (0.52) | LMNACCR5TAAR1CYP2D6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1082944-C | Novel aspartyl amide derivative and sweetener | AJINOMOTO GENERAL FOODS K K (JP) | 2002-04-17 | — | — | CN | disclosed |
| EP-0784050-B1 | Novel aspartylamide derivatives and sweeteners | AJINOMOTO KK (JP) | 2001-10-04 | — | — | EP | disclosed |
| US-6010733-A | ARTIFICIAL SWEETENER | AJINOMOTO CO., INC. (JP) | 2000-01-04 | — | — | US | disclosed |
| CN-1163261-A | Novel aspartyl amide derivative and sweetener | AJINOMOTO GENERAL FOODS INC (JP) | 1997-10-29 | — | — | CN | disclosed |
| EP-0784050-A1 | Novel aspartylamide derivatives and sweeteners | Ajinomoto Co., Inc. (JP) | 1997-07-16 | — | — | EP | disclosed |