Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263573 | 0.86 | AOC3 (0.48) | AOC3SIGMAR1LMNAESR1ESR2 | |
| SCHEMBL9000717 | 0.86 | SIGMAR1 (0.46) | SIGMAR1HTR2A | |
| SCHEMBL30312009 | 0.85 | AOC3 (0.42) | AOC3SIGMAR1LMNAESR1ESR2 | |
| SCHEMBL17027742 | 0.84 | SIGMAR1 (0.44) | SIGMAR1HTR2A | |
| SCHEMBL2419292 | 0.84 | SIGMAR1 (0.44) | SIGMAR1HTR2A | |
| SCHEMBL17027773 | 0.84 | SIGMAR1 (0.44) | SIGMAR1HTR2A | |
| SCHEMBL9276354 | 0.84 | AOC3 (0.47) | AOC3SIGMAR1LMNAESR1ESR2 | |
| SCHEMBL7775432 | 0.82 | LMNA (0.48) | AOC3SIGMAR1LMNAHRH1HTR2A | |
| SCHEMBL5890038 | 0.82 | LMNA (0.48) | AOC3SIGMAR1LMNAHRH1HTR2A | |
| SCHEMBL233438 | 0.82 | LMNA (0.48) | AOC3SIGMAR1LMNAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288120-B1 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists | PFIZER INC. | 2001-09-11 | — | — | US | disclosed |