Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1415533 | 0.85 | TAAR1 (0.43) | LMNATAAR1CYP2D6HTR2AHRH1 | |
| SCHEMBL169508 | 0.85 | LMNA (0.56) | LMNACCR5TAAR1CYP2D6MIF | |
| Ammonia Solution, Strong SCHEMBL1640901 | 0.82 | LMNA (0.54) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL8090799 | 0.82 | AOC3 (0.43) | LMNACCR5TAAR1HTR2AHRH1 | |
| SCHEMBL2240978 | 0.81 | LMNA (0.48) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL7775432 | 0.81 | LMNA (0.48) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL5890038 | 0.81 | LMNA (0.48) | LMNACCR5TAAR1CYP2D6MIF | |
| SCHEMBL12341793 | 0.80 | HTR2A (0.40) | LMNATAAR1CYP2D6HTR2AHRH1 | |
| Methylamine SCHEMBL27931105 | 0.80 | LMNA (0.52) | LMNACCR5TAAR1CYP2D6HTR2A | |
| Hypochlorous Acid SCHEMBL11415854 | 0.78 | LMNA (0.56) | LMNACCR5TAAR1CYP2D6HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632910-B1 | 3,4-DIHYDROQUINOLINONES AS FXR RECEPTOR AGONISTS | CSPC ZHONGQI PHARMACEUTICAL TECH SHIJIAZHUANG CO LTD (CN) | 2024-07-17 | — | — | EP | disclosed |
| US-9339592-B2 | Polymers of fluorinated monomers and hydrocarbon monomers | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-9289535-B2 | Polymers of fluorinated monomers and hydrocarbon monomers | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-9220816-B2 | Polymers of fluorinated monomers and hydrocarbon monomers | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2015-12-29 | — | — | US | disclosed |
| US-8529932-B2 | Polymers of fluorinated monomers and hydrocarbon monomers | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2013-09-10 | — | — | US | disclosed |
| US-8529930-B2 | Polymers of fluorinated monomers and hydrocarbon monomers | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2013-09-10 | — | — | US | disclosed |
| US-8529931-B2 | Polymers of fluorinated monomers and hydrocarbon monomers | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2013-09-10 | — | — | US | disclosed |
| US-8524266-B2 | Polymers of fluorinated monomers and hydrocarbon monomers | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2013-09-03 | — | — | US | disclosed |
| US-20100016533-A1 | POLYMERS OF FLUORINATED MONOMERS AND HYDROCARBON MONOMERS | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2010-01-21 | — | — | US | disclosed |
| US-20100003303-A1 | POLYMERS OF FLUORINATED MONOMERS AND HYDROCARBON MONOMERS | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2010-01-07 | — | — | US | disclosed |
| US-20100004396-A1 | POLYMERS OF FLUORINATED MONOMERS AND HYDROCARBON MONOMERS | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2010-01-07 | — | — | US | disclosed |
| US-20100003231-A1 | POLYMERS OF FLUORINATED MONOMERS AND HYDROCARBON MONOMERS | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2010-01-07 | — | — | US | disclosed |
| US-7604818-B2 | Polymers of fluorinated monomers and hydrocarbon monomers | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2009-10-20 | — | — | US | disclosed |
| US-20070191561-A1 | Polymers of fluorinated monomers and hydrocarbon monomers | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2007-08-16 | — | — | US | disclosed |
| EP-1053990-A2 | A method of producing an aromatic ketone and an aromatic ketone composition containing it | TORAY INDUSTRIES, INC. (JP) | 2000-11-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100003231-A1 | POLYMERS OF FLUORINATED MONOMERS AND HYDROCARBON MONOMERS | AHR, FPR1, HMBS | LMNA 3139/4885CCR5 918/4885TAAR1 617/4885 |
| US-20100003303-A1 | POLYMERS OF FLUORINATED MONOMERS AND HYDROCARBON MONOMERS | HMBS, PAH, AHR | LMNA 2278/4885CCR5 1113/4885TAAR1 714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.