Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | F13A1 | P00488 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | TGM1 | P22735 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10308981 | 0.93 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1F13A1TGM2TGM1 | |
| SCHEMBL19700749 | 0.90 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1F13A1TGM2TGM1 | |
| SCHEMBL13494190 | 0.90 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1F13A1TGM2TGM1 | |
| SCHEMBL21998139 | 0.90 | L3MBTL1 (0.56) | L3MBTL1ALDH1A1F13A1TGM2TGM1 | |
| SCHEMBL7367495 | 0.89 | ALDH1A1 (0.58) | L3MBTL1ALDH1A1F13A1TGM2TGM1 | |
| SCHEMBL25970374 | 0.88 | CCR6 (0.45) | L3MBTL1ALDH1A1F13A1TGM2TGM1 | |
| SCHEMBL22164246 | 0.88 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1F13A1TGM2TGM1 | |
| SCHEMBL30311467 | 0.88 | CCR6 (0.48) | L3MBTL1ALDH1A1F13A1TGM2TGM1 | |
| SCHEMBL28956076 | 0.87 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1MAPTHPGDSYK | |
| SCHEMBL30511020 | 0.87 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1F13A1TGM2TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0688314-B1 | PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE | HOECHST AG (DE) | 2001-10-04 | — | — | EP | disclosed |
| US-5804559-A | WATER SOLUBILITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-09-08 | — | — | US | disclosed |