Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775657 | 1.00 | RIPK1 (0.46) | RIPK1EPHX1PDE5ACES2CES1 | |
| SCHEMBL7775690 | 0.82 | EPHX1 (0.57) | EPHX1CES2CES1CYP2C19KIF11 | |
| SCHEMBL7775691 | 0.82 | EPHX1 (0.57) | EPHX1CES2CES1CYP2C19KIF11 | |
| SCHEMBL7770852 | 0.81 | RIPK1 (0.43) | RIPK1EPHX1PDE5AL3MBTL1OPRK1 | |
| SCHEMBL7776122 | 0.81 | RIPK1 (0.43) | RIPK1EPHX1PDE5AL3MBTL1OPRK1 | |
| SCHEMBL7775675 | 0.80 | EPHX1 (0.46) | RIPK1EPHX1CES2CES1CYP2C19 | |
| SCHEMBL7764706 | 0.80 | EPHX1 (0.56) | RIPK1EPHX1L3MBTL1CYP2C19TSHR | |
| SCHEMBL7764709 | 0.80 | EPHX1 (0.56) | RIPK1EPHX1L3MBTL1CYP2C19TSHR | |
| SCHEMBL28637835 | 0.79 | EPHX1 (0.45) | RIPK1EPHX1CES2CES1L3MBTL1 | |
| SCHEMBL30349638 | 0.78 | TSHR (0.45) | EPHX1L3MBTL1OPRK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127885-A2 | Optically active epoxypropionate derivatives, intermediates, and processes for their production | Tosoh Corporation (JP) | 2001-08-29 | — | — | EP | disclosed |