Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775691 | 1.00 | EPHX1 (0.57) | EPHX1MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL7764706 | 0.84 | EPHX1 (0.56) | EPHX1MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL7764709 | 0.84 | EPHX1 (0.56) | EPHX1MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL11256359 | 0.83 | FTO (0.40) | EPHX1MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL7775657 | 0.82 | RIPK1 (0.46) | EPHX1CYP2C19TSHRKIF11CES2 | |
| SCHEMBL7775658 | 0.82 | RIPK1 (0.46) | EPHX1CYP2C19TSHRKIF11CES2 | |
| SCHEMBL7776125 | 0.79 | EPHX1 (0.53) | EPHX1MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL8550629 | 0.78 | EPHX1 (0.69) | EPHX1MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL9255795 | 0.78 | EPHX1 (0.69) | EPHX1MEN1KMT2ATP53CYP1A2 | |
| SCHEMBL7771291 | 0.78 | EPHX1 (0.69) | EPHX1MEN1KMT2ATP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127885-A2 | Optically active epoxypropionate derivatives, intermediates, and processes for their production | Tosoh Corporation (JP) | 2001-08-29 | — | — | EP | disclosed |