Nitrogen

Nitrogen

SCHEMBL7775733

ClN(Cl)c1ccccc1.F[B-](F)(F)F.N#[NH+]

nearest known ligand 0.31

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.31
NPSR1 Q6W5P4 2/20 0.31
ALOX15 P16050 1/20 0.31
HTT P42858 2/20 0.30
KMT2A Q03164 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
NPC1 O15118 1/20 0.30
POLB P06746 1/20 0.30
RAB9A P51151 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30
KDM4E B2RXH2 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
MAPT P10636 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrogen SCHEMBL4342761 0.82 ALDH1A1 (0.38) ALDH1A1NPSR1ALOX15HTTKMT2A
SCHEMBL18812 0.82
Benzene SCHEMBL27358958 0.82 ALDH1A1 (0.41) ALDH1A1NPSR1ALOX15HTTKMT2A
SCHEMBL28381795 0.79 ALDH1A1 (0.39) ALDH1A1NPSR1ALOX15HTTKMT2A
Hydrochloric Acid SCHEMBL8530750 0.79 ALDH1A1 (0.39) ALDH1A1NPSR1ALOX15HTTKMT2A
Nitrogen SCHEMBL11320577 0.76 ALDH1A1 (0.46) ALDH1A1ALOX15HTTKMT2ATDP1
Biphenyl SCHEMBL28211636 0.73 ALDH1A1 (0.60) ALDH1A1TDP1NPC1RAB9ACA1
Chlorobenzene SCHEMBL10967244 0.72 TSHR (0.61) ALDH1A1NPC1RAB9AKDM4ECYP1A2
Diethylaniline SCHEMBL11653531 0.71 TSHR (0.53) ALDH1A1HTTKMT2ATDP1NPC1
Toluene SCHEMBL28853002 0.70 ACHE (0.58) ALDH1A1NPSR1ALOX15HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0918220-B1 Diazonium ion assay reagents and methods for their use ROCHE DIAGNOSTICS CORP (US) 2001-08-01 EP disclosed
US-5935861-A MIXTURE OF SOLUBILIZER AND 2-METHYL-3-NITROANILINE DIAZONIUM ION; FOR SPECTROPHOTOMETRIC DETECTION AND QUANTIFICATION OF BILIRUBIN AND DIAGNOSIS OF LIVER, GALL BLADDER AND INTESTINAL DISORDERS BOEHRINGER MANNHEIM CORPORATION (US) 1999-08-10 US disclosed
EP-0918220-A1 Diazonium ion assay reagents and methods for their use BOEHRINGER MANNHEIM CORPORATION (US) 1999-05-26 EP disclosed