Methacrylic Acid

Methacrylic Acid

SCHEMBL7775752

C=C(C)C(=O)O.CCCCCCCCOC=C(C)C(=O)O.OCC(O)CO

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
USP2 O75604 1/20 0.42
PLA2G2C Q5R387 1/20 0.40
KDM4E B2RXH2 1/20 0.38
DUSP3 P51452 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 1/20 0.38
DGKA P23743 1/20 0.36
CES2 O00748 1/20 0.34
HCAR2 Q8TDS4 1/20 0.34
GPR84 Q9NQS5 2/20 0.33
PLA2G4B P0C869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL5378370 0.89 USP2 (0.33) USP2
SCHEMBL28126163 0.84 CES2 (0.46) TSHRCES2HCAR2GPR84
SCHEMBL3388405 0.84 CES2 (0.46) TSHRCES2HCAR2GPR84
SCHEMBL898727 0.82 HCAR2 (0.43) TSHRCES2HCAR2
SCHEMBL898728 0.82 HCAR2 (0.43) TSHRCES2HCAR2
Glycolic Acid SCHEMBL10531852 0.81 CES2 (0.41) TSHRMEN1KMT2ACES2HCAR2
Methacrylic Acid SCHEMBL9069150 0.77 TSHR (0.35) TSHRHCAR2
Methacrylic Acid SCHEMBL3688393 0.77
SCHEMBL809305 0.77 ALDH1A1 (0.45) TSHRCES2HCAR2
SCHEMBL809306 0.77 ALDH1A1 (0.45) TSHRCES2HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0801335-B1 Magnetic coated carrier, two-component type developer and developing method CANON KK (JP) 2001-08-29 EP disclosed
US-6165663-A Magnetic coated carrier two-component type developer and developing method CANON KABUSHIKI KAISHA (JP) 2000-12-26 US disclosed
EP-0801335-A1 Magnetic coated carrier, two-component type developer and developing method CANON KABUSHIKI KAISHA (JP) 1997-10-15 EP disclosed