SCHEMBL7775844

SCHEMBL7775844

Cc1cc(C)c(Cc2ccc(Cc3ccc(O)c(C(=O)O)c3)cc2)c(C)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KLKB1 P03952 1/20 0.68
CTSB P07858 1/20 0.68
MMP9 P14780 1/20 0.68
DNMT1 P26358 1/20 0.68
DNMT3B Q9UBC3 1/20 0.68
DNMT3L Q9UJW3 1/20 0.68
DNMT3A Q9Y6K1 1/20 0.68
HNF4A P41235 1/20 0.65
CSNK2A1 P68400 1/20 0.51
LCK P06239 2/20 0.50
ACMSD Q8TDX5 1/20 0.50
THRA P10827 5/20 0.49
THRB P10828 5/20 0.49
KAT8 Q9H7Z6 2/20 0.48
HMGB1 P09429 1/20 0.47
CXCL12 P48061 1/20 0.47
MCL1 Q07820 3/20 0.46
ESR1 P03372 1/20 0.46
ESR2 Q92731 1/20 0.46
ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9496912 0.99 KLKB1 (0.66) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL27645320 0.88 KLKB1 (0.67) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL9651461 0.86 KLKB1 (0.79) KLKB1CTSBMMP9DNMT1DNMT3B
Zinc Ion SCHEMBL9496903 0.86 KLKB1 (0.47) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL23265352 0.83 KLKB1 (0.79) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL29414416 0.82 KLKB1 (1.00) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL160646 0.82 KLKB1 (1.00) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL9250700 0.79 KLKB1 (0.85) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL27396608 0.79 HNF4A (1.00) KLKB1CTSBMMP9DNMT1DNMT3B
SCHEMBL5446640 0.79 HNF4A (1.00) KLKB1CTSBMMP9DNMT1DNMT3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885745-B1 Thermosensitive recording sheet set for preservation temperature control and method of using the sheet set OJI PAPER CO (JP) 2001-09-19 EP disclosed
US-5994262-A MULTILAYER; RECORDING SHEET CONTAINING ZINC SALT OF A SALICYLIC ACID; ADHESIVE LAYER CONTAINING A LEUCO DYE AND AN ESTER; TEMPERATURE CONTROL OJI PAPER CO., LTD. (JP) 1999-11-30 US disclosed
EP-0428994-B1 Method for preparing aqueous dispersion of developer and pressure-sensitive recording paper SANKO KAIHATSU KAGAKU KENK (JP) 1999-03-10 EP disclosed
EP-0885745-A1 Thermosensitive recording sheet set for preservation temperature control and method of using the sheet set Oji Paper Co., Ltd. (JP) 1998-12-23 EP disclosed
US-5647896-A MULTIVALENT SALT OF A SALICYLIC ACID DERIVATIVE, SULFONATED PHENOL MITSUI TOATSU CHEMICALS, INC. (JP) 1997-07-15 US disclosed
EP-0714785-A1 Sulfonated phenol (salt) containing color-developing agents and color-developing sheets MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-06-05 EP disclosed
US-5328884-A Salicylic acid salt,and amide or sulfonamide as developer KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-07-12 US disclosed
US-5250108-A Mixture of salicylic acid salt, amide and sulfonamide compounds KANZAKI PAPER MANUFACTURING CO. LTD. (JP) 1993-10-05 US disclosed
US-5204190-A Nuclear-substituted salicyclic acid salt emulsified and disperions in aqueous solution of acyrlamide acrylamide copolymer SANKO KAIHATSU KAGAKU KENYUSHO (JP) 1993-04-20 US disclosed
US-5164001-A Salicylic salt, acrylamide copolymer SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1992-11-17 US disclosed
US-5141557-A Mixture of benzoic acid salt, anionic surfactant, and novolak phenolic resin BROTHER KOGYO KABUSHIKI KAISHA (JP) 1992-08-25 US disclosed
EP-0428994-A1 Method for preparing aqueous dispersion of developer and pressure-sensitive recording paper Sanko Kaihatsu Kagaku Kenkyusho (JP) 1991-05-29 EP disclosed