Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.67 |
| ▸ | CTSB | P07858 | 1/20 | 0.67 |
| ▸ | MMP9 | P14780 | 1/20 | 0.67 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.67 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.67 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.67 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.67 |
| ▸ | HNF4A | P41235 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 2/20 | 0.53 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7775844 | 0.88 | KLKB1 (0.68) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL9496912 | 0.87 | KLKB1 (0.66) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL23265352 | 0.82 | KLKB1 (0.79) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL27733443 | 0.81 | ALOX5 (0.54) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL160646 | 0.81 | KLKB1 (1.00) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL29414416 | 0.81 | KLKB1 (1.00) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL27666556 | 0.80 | HSD17B1 (0.43) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL285291 | 0.79 | THRB (0.76) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL9651461 | 0.79 | KLKB1 (0.79) | KLKB1CTSBMMP9DNMT1DNMT3B | |
| SCHEMBL9250700 | 0.78 | KLKB1 (0.85) | KLKB1CTSBMMP9DNMT1DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189248-A | Novel phosphorus-containing thyromimetics | METABASIS THERAPEUTICS INC (US) | 2008-05-28 | — | — | CN | disclosed |
| CN-101180097-A | Novel phosphinic acid-containing thyromimetics | METABASIS THERAPEUTICS INC (US) | 2008-05-14 | — | — | CN | disclosed |
| CN-1882327-A | Novel phosphorus-containing thyromimetics | METABASIS THERAPEUTICS INC (US) | 2006-12-20 | — | — | CN | disclosed |