Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4480218 | 0.85 | SLC6A4 (0.36) | SLC6A4KDM1AADRA1DADRA1AADRA1B | |
| SCHEMBL11614041 | 0.80 | KDM1A (0.38) | SLC6A4KDM1AADRA1DADRA1AADRA1B | |
| SCHEMBL5248281 | 0.80 | KDM1A (0.38) | SLC6A4KDM1AADRA1DADRA1AADRA1B | |
| SCHEMBL2155195 | 0.80 | KDM1A (0.43) | SLC6A4KDM1AADRA1DADRA1AADRA1B | |
| SCHEMBL7775994 | 0.77 | KDM1A (0.38) | SLC6A4KDM1ADRD2IDO1SLC6A2 | |
| SCHEMBL10476854 | 0.77 | KDM1A (0.38) | SLC6A4KDM1AADRA1DADRA1AADRA1B | |
| SCHEMBL7999943 | 0.75 | KDM1A (0.39) | SLC6A4KDM1ADRD2IDO1SLC6A2 | |
| SCHEMBL20597643 | 0.73 | HSD11B1 (0.37) | SLC6A4KDM1ADRD2IDO1SLC6A2 | |
| SCHEMBL14931728 | 0.73 | IDO1 (0.36) | SLC6A4KDM1ADRD2IDO1L3MBTL1 | |
| SCHEMBL391322 | 0.72 | EGFR (0.35) | SLC6A4KDM1ADRD2IDO1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675095-B1 | Process for preparing 2,2'-bis(halogenomethyl)-1,1'-binaphthalene | HOECHST AG (DE) | 1999-03-24 | — | — | EP | disclosed |
| EP-0675095-A1 | Process for preparing 2,2'-bis(halogenomethyl)-1,1'-binaphthalene | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-04 | — | — | EP | disclosed |