Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118007 | 0.98 | MEN1 (0.41) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL11789798 | 0.85 | SMN1; SMN2 (0.37) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL11304283 | 0.84 | MEN1 (0.35) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL10852041 | 0.82 | SMN1; SMN2 (0.39) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL11728875 | 0.82 | LMNA (0.40) | MEN1KMT2ACYP1A2PDE4BPDE4D | |
| SCHEMBL17584792 | 0.78 | LTA4H (0.41) | MEN1KMT2ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL11443302 | 0.78 | MEN1 (0.39) | MEN1KMT2ACYP1A2POLBSMN1; SMN2 | |
| SCHEMBL582039 | 0.74 | MEN1 (0.52) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL10969660 | 0.74 | MAPK8 (0.43) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL11737692 | 0.74 | LMNA (0.40) | CYP1A2MAPK1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603893-B1 | Process for the preparation of 2-ethoxy-4,6-dihydroxy pyrimidin or their alkaline salts | SUEDDEUTSCHE KALKSTICKSTOFF (DE) | 2001-08-08 | — | — | EP | disclosed |
| EP-0603893-A1 | Process for the preparation of 2-ethoxy-4,6-dihydroxy pyrimidin or their alkaline salts | SKW Trostberg Aktiengesellschaft (DE) | 1994-06-29 | — | — | EP | disclosed |