Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776188 | 0.98 | MEN1 (0.39) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL11789798 | 0.87 | SMN1; SMN2 (0.37) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL11304283 | 0.86 | MEN1 (0.35) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL10852041 | 0.84 | SMN1; SMN2 (0.39) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL11728875 | 0.84 | LMNA (0.40) | MEN1KMT2ACYP1A2PDE4BPDE4D | |
| SCHEMBL17584792 | 0.80 | LTA4H (0.41) | MEN1KMT2ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL11443302 | 0.80 | MEN1 (0.39) | MEN1KMT2ACYP1A2POLBSMN1; SMN2 | |
| SCHEMBL582039 | 0.76 | MEN1 (0.52) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL10969660 | 0.76 | MAPK8 (0.43) | MEN1KMT2ACYP1A2POLBPDE4B | |
| SCHEMBL11737692 | 0.76 | LMNA (0.40) | CYP1A2MAPK1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114262300-A | Preparation method of 2-ethoxy-4, 6-difluoropyrimidine | 浙江伟锋药业有限公司 | 2022-04-01 | — | — | CN | claimed |
| CN-111303045-A | Production process of 2-ethoxy-4, 6-difluoropyrimidine | 温州大学 | 2020-06-19 | — | — | CN | claimed |
| EP-1042303-B1 | CHLOROPYRIMIDINE PROCESS | DOW AGROSCIENCES LLC (US) | 2003-02-05 | — | — | EP | claimed |
| EP-0603893-B1 | Process for the preparation of 2-ethoxy-4,6-dihydroxy pyrimidin or their alkaline salts | SUEDDEUTSCHE KALKSTICKSTOFF (DE) | 2001-08-08 | — | — | EP | claimed |
| US-6066734-A | Chloropyrimidine process | DOW AGROSCIENCES LLC (US) | 2000-05-23 | — | — | US | claimed |
| US-5552546-A | Process for the preparation of 2-ethoxy-4,6-dihydroxypyrimidine | DOWELANCO (US) | 1996-09-03 | — | — | US | claimed |
| US-5463055-A | Reacting O-ethylisourea (or salt) with an alcoholate and/or a malonic acid dialkyl ester derivative, then acidification, desalting | SKW TROSTBERG AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | claimed |
| EP-0603893-A1 | Process for the preparation of 2-ethoxy-4,6-dihydroxy pyrimidin or their alkaline salts | SKW Trostberg Aktiengesellschaft (DE) | 1994-06-29 | — | — | EP | claimed |
| CN-114262300-A | Preparation method of 2-ethoxy-4, 6-difluoropyrimidine | 浙江伟锋药业有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-114262300-A | Preparation method of 2-ethoxy-4, 6-difluoropyrimidine | 浙江伟锋药业有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-106866547-B | Synthesis method of 2-ethoxy-4, 6-dichloropyrimidine | 江苏省农用激素工程技术研究中心有限公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-111303045-A | Production process of 2-ethoxy-4, 6-difluoropyrimidine | 温州大学 | 2020-06-19 | — | — | CN | disclosed |
| US-8158787-B2 | Process for producing trichloropyrimidine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20100160630-A1 | PROCESS FOR PRODUCING TRICHLOROPYRIMIDINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| US-5463055-A | Reacting O-ethylisourea (or salt) with an alcoholate and/or a malonic acid dialkyl ester derivative, then acidification, desalting | SKW TROSTBERG AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0603893-A1 | Process for the preparation of 2-ethoxy-4,6-dihydroxy pyrimidin or their alkaline salts | SKW Trostberg Aktiengesellschaft (DE) | 1994-06-29 | — | — | EP | disclosed |
| EP-0603893-A1 | Process for the preparation of 2-ethoxy-4,6-dihydroxy pyrimidin or their alkaline salts | SKW Trostberg Aktiengesellschaft (DE) | 1994-06-29 | — | — | EP | disclosed |
| EP-0603893-A1 | Process for the preparation of 2-ethoxy-4,6-dihydroxy pyrimidin or their alkaline salts | SKW Trostberg Aktiengesellschaft (DE) | 1994-06-29 | — | — | EP | disclosed |
| US-4059696-A | INSECTICIDE, MITICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-22 | — | — | US | disclosed |
| US-4045561-A | Pesticidal pyrimidinyl phosphorus esters | SANDOZ LTD. (CH) | 1977-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160630-A1 | PROCESS FOR PRODUCING TRICHLOROPYRIMIDINE COMPOUND | DPYD, TYMP, TST | MEN1 4481/4885KMT2A 3104/4885CYP1A2 777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.