Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 4/20 | 0.32 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9413638 | 1.00 | LMNA (0.44) | LMNAALDH1A1SMN1; SMN2ADRA1AHPGD | |
| SCHEMBL9413642 | 1.00 | LMNA (0.44) | LMNAALDH1A1SMN1; SMN2ADRA1AHPGD | |
| SCHEMBL9407259 | 0.99 | LMNA (0.45) | LMNAALDH1A1SMN1; SMN2ADRA1AHPGD | |
| SCHEMBL11859680 | 0.86 | LMNA (0.46) | LMNAALDH1A1SMN1; SMN2HPGDRECQL | |
| SCHEMBL8780022 | 0.86 | LMNA (0.41) | LMNAALDH1A1HPGDRECQLEPHX2 | |
| SCHEMBL6362210 | 0.86 | LMNA (0.41) | LMNAALDH1A1HPGDRECQLEPHX2 | |
| SCHEMBL6270981 | 0.84 | LMNA (0.44) | LMNAALDH1A1SMN1; SMN2HPGDRECQL | |
| SCHEMBL12845801 | 0.83 | HPGD (0.51) | LMNAALDH1A1SMN1; SMN2HPGDRECQL | |
| SCHEMBL9414491 | 0.80 | LMNA (0.43) | LMNAALDH1A1SMN1; SMN2HPGDRECQL | |
| SCHEMBL6361849 | 0.80 | LMNA (0.51) | LMNAALDH1A1SMN1; SMN2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603917-A1 | Iodinated agents and X-ray imaging compositions containing them | NanoSystems L.L.C. (US) | 1994-06-29 | — | — | EP | claimed |
| EP-1126884-A2 | RADIODENSE COMPOSITIONS | THE GENERAL HOSPITAL CORPORATION (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2000025829-A2 | RADIODENSE COMPOSITIONS | THE GENERAL HOSPITAL CORPORATION (US) | 2000-05-11 | — | — | WO | disclosed |
| US-5346688-A | Medical x-ray diagnostic imaging | STERLING WINTHROP INC. (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0603917-A1 | Iodinated agents and X-ray imaging compositions containing them | NanoSystems L.L.C. (US) | 1994-06-29 | — | — | EP | disclosed |