Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PTPRB | P23467 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776203 | 0.99 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1HPGDRECQL | |
| SCHEMBL9413642 | 0.99 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1HPGDRECQL | |
| SCHEMBL9413638 | 0.99 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1HPGDRECQL | |
| SCHEMBL11859680 | 0.84 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1HPGDRECQL | |
| SCHEMBL6362210 | 0.84 | LMNA (0.41) | LMNAALDH1A1HPGDRECQLTSHR | |
| SCHEMBL8780022 | 0.84 | LMNA (0.41) | LMNAALDH1A1HPGDRECQLTSHR | |
| SCHEMBL12845801 | 0.84 | HPGD (0.51) | LMNASMN1; SMN2ALDH1A1HPGDRECQL | |
| SCHEMBL9414494 | 0.83 | DGKA (0.41) | LMNAALDH1A1HPGDRECQLEPHX2 | |
| SCHEMBL6270981 | 0.82 | LMNA (0.44) | LMNASMN1; SMN2ALDH1A1HPGDRECQL | |
| SCHEMBL9414491 | 0.81 | LMNA (0.43) | LMNASMN1; SMN2ALDH1A1HPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0603917-A1 | Iodinated agents and X-ray imaging compositions containing them | NanoSystems L.L.C. (US) | 1994-06-29 | — | — | EP | claimed |
| JP-6211764-A | — | — | None | — | — | JP | disclosed |
| US-5346688-A | Medical x-ray diagnostic imaging | STERLING WINTHROP INC. (US) | 1994-09-13 | — | — | US | disclosed |
| JP-H06211764-A | IODINATED AROMATIC COMPOUND USEFUL AS WETTING AGENT, AND X-RAY IMAGING COMPOSITION CONTAINING THE COMPOUND | STERLING WINTHROP INC | 1994-08-02 | — | — | JP | disclosed |
| EP-0603917-A1 | Iodinated agents and X-ray imaging compositions containing them | NanoSystems L.L.C. (US) | 1994-06-29 | — | — | EP | disclosed |