Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ESR1 | P03372 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11859680 | 0.85 | LMNA (0.46) | HPGDRECQLLMNAESR1ALDH1A1 | |
| SCHEMBL9852571 | 0.84 | LMNA (0.51) | HPGDRECQLLMNAALDH1A1TSHR | |
| SCHEMBL332859 | 0.84 | LMNA (0.54) | HPGDLMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9413642 | 0.83 | LMNA (0.44) | HPGDRECQLLMNAESR1ALDH1A1 | |
| SCHEMBL21911756 | 0.83 | LMNA (0.44) | HPGDRECQLLMNAESR1ALDH1A1 | |
| SCHEMBL7776203 | 0.83 | LMNA (0.44) | HPGDRECQLLMNAESR1ALDH1A1 | |
| SCHEMBL6362210 | 0.83 | LMNA (0.41) | HPGDRECQLLMNAALDH1A1TSHR | |
| SCHEMBL8780022 | 0.83 | LMNA (0.41) | HPGDRECQLLMNAALDH1A1TSHR | |
| SCHEMBL8934434 | 0.82 | CYP1A2 (0.41) | HPGDRECQLLMNAALDH1A1TSHR | |
| SCHEMBL21783784 | 0.81 | LMNA (0.47) | LMNATSHRL3MBTL1RAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110052503-A1 | BIODEGRADABLE CONTRAST AGENTS | IOPHARMA TECHNOLOGIES AB (SE) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110052503-A1 | BIODEGRADABLE CONTRAST AGENTS | CNDP2, RXFP1, RXFP3 | HPGD 206/4885RECQL 418/4885LMNA 3913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.