Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776155 | 0.96 | KMT2A (0.53) | MEN1KMT2AABCB1HTR2AMAPT | |
| SCHEMBL7388398 | 0.89 | ABCB1 (0.57) | MEN1KMT2AABCB1HTR2AMAPT | |
| SCHEMBL5901095 | 0.85 | KDM4E (0.62) | MEN1KMT2AABCB1MAPTPOLB | |
| SCHEMBL5749820 | 0.84 | HTR2A (0.64) | MEN1KMT2AABCB1HTR2AMAPT | |
| SCHEMBL7776183 | 0.83 | GPR119 (0.47) | MEN1KMT2AABCB1HTR2AMAPT | |
| SCHEMBL7769768 | 0.83 | GPR119 (0.47) | MEN1KMT2AABCB1HTR2AMAPT | |
| SCHEMBL7776181 | 0.82 | GPR119 (0.48) | MEN1KMT2AABCB1HTR2AMAPT | |
| SCHEMBL7389832 | 0.79 | ABCB1 (0.56) | MEN1KMT2AABCB1HTR2AMAPT | |
| SCHEMBL23202714 | 0.77 | ATF4 (0.62) | MEN1KMT2AABCB1HTR2ACACNA1G | |
| SCHEMBL21819438 | 0.77 | ATF4 (0.62) | MEN1KMT2AABCB1HTR2ACACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0574906-B1 | Piperazine and homopiperazine derivatives, pharmaceutical compositions containing them and process for preparing the same | NISSHIN FLOUR MILLING CO (JP) | 2001-08-22 | — | — | EP | disclosed |
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| US-5380724-A | Inhibitors of lipid peroxidation | GYOGYSZERKUTATO INTEZET KFT (HU) | 1995-01-10 | — | — | US | disclosed |
| EP-0574906-A2 | Piperazine and homopiperazine derivatives, pharmaceutical compositions containing them and process for preparing the same | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1993-12-22 | — | — | EP | disclosed |